A comprehensive review of the potential use of green tea polyphenols in the management of COVID‐19

TE Tallei, Fatimawali, NJ Niode… - Evidence‐Based …, 2021 - Wiley Online Library
Green tea is produced from Camellia sinensis (L.) buds and leaves that have not gone
through the oxidation and withering processes used to produce black and oolong teas. It …

[HTML][HTML] Inhibition of the main protease of SARS-CoV-2 (Mpro) by repurposing/designing drug-like substances and utilizing nature's toolbox of bioactive compounds

I Antonopoulou, E Sapountzaki, U Rova… - Computational and …, 2022 - Elsevier
The emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
has resulted in a long pandemic, with numerous cases and victims worldwide and enormous …

Impact of Early Pandemic Stage Mutations on Molecular Dynamics of SARS-CoV-2 Mpro

O Sheik Amamuddy, GM Verkhivker… - Journal of chemical …, 2020 - ACS Publications
A new coronavirus (SARS-CoV-2) is a global threat to world health and economy. Its dimeric
main protease (Mpro), which is required for the proteolytic cleavage of viral precursor …

Possible use of phytochemicals for recovery from COVID-19-induced anosmia and ageusia

S Koyama, K Kondo, R Ueha, H Kashiwadani… - International Journal of …, 2021 - mdpi.com
The year 2020 became the year of the outbreak of coronavirus, SARS-CoV-2, which
escalated into a worldwide pandemic and continued into 2021. One of the unique symptoms …

Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2

K Gao, R Wang, J Chen, L Cheng, J Frishcosy… - Chemical …, 2022 - ACS Publications
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

Identification and molecular mechanism of novel immunomodulatory peptides from gelatin hydrolysates: Molecular docking, dynamic simulation, and cell experiments

Z Yu, Y Wang, D Shuian, J Liu… - Journal of Agricultural and …, 2023 - ACS Publications
The purpose of this study was to identify donkey-hide gelatin-derived immunomodulatory
peptides targeting Toll-like receptor 4-myeloid differentiation 2 (TLR4-MD2) and elucidate …

Pharmacoinformatics and hypothetical studies on allicin, curcumin, and gingerol as potential candidates against COVID-19-associated proteases

BJ Oso, AO Adeoye, IF Olaoye - Journal of Biomolecular Structure …, 2022 - Taylor & Francis
Medicinal plants have been known to provide the essential raw material for the majority of
antiviral drugs. This study demonstrated the putative inhibitory potential of curcumin, allicin …

Identification of alkaloids from Justicia adhatoda as potent SARS CoV-2 main protease inhibitors: An in silico perspective

R Ghosh, A Chakraborty, A Biswas… - Journal of molecular …, 2021 - Elsevier
The COVID-19 pandemic, caused by SARS CoV-2, is responsible for millions of death
worldwide. No approved/proper therapeutics is currently available which can effectively …

Natural products for the prevention and control of the COVID-19 pandemic: sustainable bioresources

RK Singla, X He, H Chopra, C Tsagkaris… - Frontiers in …, 2021 - frontiersin.org
Background: The world has been unprecedentedly hit by a global pandemic which broke the
record of deadly pandemics that faced humanity ever since its existence. Even kids are well …

[HTML][HTML] An overview of potential inhibitors targeting non-structural proteins 3 (PLpro and Mac1) and 5 (3CLpro/Mpro) of SARS-CoV-2

F Yan, F Gao - Computational and structural biotechnology journal, 2021 - Elsevier
There is an urgent need to develop effective treatments for coronavirus disease 2019
(COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS …