HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment
In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …
individuals. Most importantly, the development and deployment of combination antiretroviral …
Cognitive disorders in people living with HIV
High rates of cognitive disorders in antiretroviral-treated people living with HIV have been
described worldwide. The exact prevalence of such cognitive disorders is determined by the …
described worldwide. The exact prevalence of such cognitive disorders is determined by the …
[HTML][HTML] Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: a cross-sectional study
M Gisslén, RW Price, U Andreasson, N Norgren… - …, 2016 - thelancet.com
Background Cerebrospinal fluid (CSF) neurofilament light chain protein (NFL) is a sensitive
marker of neuronal injury in a variety of neurodegenerative conditions, including the CNS …
marker of neuronal injury in a variety of neurodegenerative conditions, including the CNS …
Neuropathogenesis of HIV: from initial neuroinvasion to HIV-associated neurocognitive disorder (HAND)
Z Zayyad, S Spudich - Current Hiv/Aids Reports, 2015 - Springer
Early in the HIV epidemic, the central nervous system (CNS) was recognized as a target of
infection and injury in the advanced stages of disease. Though the most severe forms of HIV …
infection and injury in the advanced stages of disease. Though the most severe forms of HIV …
Neuroinflammation in treated HIV-positive individuals: a TSPO PET study
Objective: To explore the effects of microglial activation on brain function and structure, and
its relationship with peripheral inflammatory markers, in treated, HIV-positive individuals …
its relationship with peripheral inflammatory markers, in treated, HIV-positive individuals …
Neurofilament light chain protein as a marker of neuronal injury: review of its use in HIV-1 infection and reference values for HIV-negative controls
A Yilmaz, K Blennow, L Hagberg… - Expert review of …, 2017 - Taylor & Francis
Introduction: Several CSF biomarkers of neuronal injury have been studied in people living
with HIV. At this time, the most useful is the light subunit of the neurofilament protein (NFL) …
with HIV. At this time, the most useful is the light subunit of the neurofilament protein (NFL) …
[HTML][HTML] Depression among Patients with HIV/AIDS: Research Development and Effective Interventions (GAPRESEARCH)
Depression in people living with HIV (PLWH) has become an urgent issue and has attracted
the attention of both physicians and epidemiologists. Currently, 39% of HIV patients are …
the attention of both physicians and epidemiologists. Currently, 39% of HIV patients are …
Monocytes mediate HIV neuropathogenesis: mechanisms that contribute to HIV associated neurocognitive disorders
DW Williams, M Veenstra, PJ Gaskill… - Current HIV …, 2014 - ingentaconnect.com
HIV infected people are living longer due to the success of combined antiretroviral therapy
(cART). However, greater than 40-70% of HIV infected individuals develop HIV associated …
(cART). However, greater than 40-70% of HIV infected individuals develop HIV associated …
Blood neuron-derived exosomes as biomarkers of cognitive impairment in HIV
B Sun, P Dalvi, L Abadjian, N Tang, L Pulliam - Aids, 2017 - journals.lww.com
Objective: To investigate proteins associated with neuronal damage in plasma neuron-
derived exosomes (NDE) of HIV-infected study participants as a liquid biomarker for …
derived exosomes (NDE) of HIV-infected study participants as a liquid biomarker for …
HIV-associated neurocognitive disorder
RC Smail, BJ Brew - Handbook of clinical neurology, 2018 - Elsevier
Human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND) affects
roughly half the HIV-positive population. The symptoms of cognitive slowing, poor …
roughly half the HIV-positive population. The symptoms of cognitive slowing, poor …