Porcine reproductive and respiratory syndrome virus (PRRSV): pathogenesis and interaction with the immune system

JK Lunney, Y Fang, A Ladinig, N Chen… - Annual review of …, 2016 - annualreviews.org
This review addresses important issues of porcine reproductive and respiratory syndrome
virus (PRRSV) infection, immunity, pathogenesis, and control. Worldwide, PRRS is the most …

Translation elongation and recoding in eukaryotes

TE Dever, JD Dinman, R Green - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
In this review, we highlight the current understanding of translation elongation and recoding
in eukaryotes. In addition to providing an overview of the process, recent advances in our …

Viral RNA structure-based strategies to manipulate translation

ZA Jaafar, JS Kieft - Nature Reviews Microbiology, 2019 - nature.com
Viruses must co-opt the cellular translation machinery to produce progeny virions.
Eukaryotic viruses have evolved a variety of ways to manipulate the cellular translation …

[HTML][HTML] PRRSV structure, replication and recombination: Origin of phenotype and genotype diversity

MA Kappes, KS Faaberg - Virology, 2015 - Elsevier
Porcine reproductive and respiratory disease virus (PRRSV) has the intrinsic ability to adapt
and evolve. After 25 years of study, this persistent pathogen has continued to frustrate efforts …

Arterivirus molecular biology and pathogenesis

EJ Snijder, M Kikkert, Y Fang - Journal of General …, 2013 - microbiologyresearch.org
Arteriviruses are positive-stranded RNA viruses that infect mammals. They can cause
persistent or asymptomatic infections, but also acute disease associated with a respiratory …

Translational control in virus-infected cells

N Stern-Ginossar, SR Thompson… - Cold Spring …, 2019 - cshperspectives.cshlp.org
As obligate intracellular parasites, virus reproduction requires host cell functions. Despite
variations in genome size and configuration, nucleic acid composition, and their repertoire of …

Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use

JF Atkins, G Loughran, PR Bhatt, AE Firth… - Nucleic acids …, 2016 - academic.oup.com
Genetic decoding is not 'frozen'as was earlier thought, but dynamic. One facet of this is
frameshifting that often results in synthesis of a C-terminal region encoded by a new frame …

Key gaps in the knowledge of the porcine respiratory reproductive syndrome virus (PRRSV)

S Montaner-Tarbes, HA Del Portillo… - Frontiers in veterinary …, 2019 - frontiersin.org
The porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most
important swine diseases in the world. It is causing an enormous economic burden due to …

Molecular and cellular mechanisms for PRRSV pathogenesis and host response to infection

TQ An, JN Li, CM Su, D Yoo - Virus research, 2020 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous
amounts of economic losses to the swine industry for more than three decades, but its …

Live porcine reproductive and respiratory syndrome virus vaccines: current status and future direction

GJ Renukaradhya, XJ Meng, JG Calvert, M Roof… - Vaccine, 2015 - Elsevier
Porcine reproductive and respiratory syndrome (PRRS) caused by PRRS virus (PRRSV)
was reported in the late 1980s. PRRS still is a huge economic concern to the global pig …