Visible-light and near-infrared fluorescence and surface-enhanced Raman scattering point-of-care sensing and bio-imaging: A review

Y Hang, J Boryczka, N Wu - Chemical Society Reviews, 2022 - pubs.rsc.org
This review article deals with the concepts, principles and applications of visible-light and
near-infrared (NIR) fluorescence and surface-enhanced Raman scattering (SERS) in in vitro …

Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases

W Yang, Y Cong - Cellular & molecular immunology, 2021 - nature.com
The gut microbiota has a critical role in the maintenance of immune homeostasis. Alterations
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …

The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine

D Yu, NE Richardson, CL Green, AB Spicer… - Cell metabolism, 2021 - cell.com
Low-protein diets promote metabolic health in rodents and humans, and the benefits of low-
protein diets are recapitulated by specifically reducing dietary levels of the three branched …

Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 …

F Vanweert, P Schrauwen, E Phielix - Nutrition & diabetes, 2022 - nature.com
Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …

Metabolites as regulators of insulin sensitivity and metabolism

Q Yang, A Vijayakumar, BB Kahn - Nature reviews Molecular cell …, 2018 - nature.com
The cause of insulin resistance in obesity and type 2 diabetes mellitus (T2DM) is not limited
to impaired insulin signalling but also involves the complex interplay of multiple metabolic …

Decreased consumption of branched-chain amino acids improves metabolic health

L Fontana, NE Cummings, SIA Apelo, JC Neuman… - Cell reports, 2016 - cell.com
Summary Protein-restricted (PR), high-carbohydrate diets improve metabolic health in
rodents, yet the precise dietary components that are responsible for these effects have not …

Restoration of metabolic health by decreased consumption of branched‐chain amino acids

NE Cummings, EM Williams, I Kasza… - The Journal of …, 2018 - Wiley Online Library
Key points We recently found that feeding healthy mice a diet with reduced levels of
branched-chain amino acids (BCAAs), which are associated with insulin resistance in both …

Targeting BCAA catabolism to treat obesity-associated insulin resistance

M Zhou, J Shao, CY Wu, L Shu, W Dong, Y Liu… - Diabetes, 2019 - Am Diabetes Assoc
Recent studies implicate a strong association between elevated plasma branched-chain
amino acids (BCAAs) and insulin resistance (IR). However, a causal relationship and …

Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis

MF Bustamante, R Garcia-Carbonell… - Arthritis research & …, 2017 - Springer
An increasing number of studies show how changes in intracellular metabolic pathways
alter tumor and immune cell function. However, little information about metabolic changes in …

The role of BCAA metabolism in metabolic health and disease

BH Choi, S Hyun, SH Koo - Experimental & Molecular Medicine, 2024 - nature.com
It has long been postulated that dietary restriction is beneficial for ensuring longevity and
extending the health span of mammals, including humans. In particular, a reduction in …