Acanthamoeba spp. as Agents of Disease in Humans

F Marciano-Cabral, G Cabral - Clinical microbiology reviews, 2003 - Am Soc Microbiol
Acanthamoeba spp. are free-living amebae that inhabit a variety of air, soil, and water
environments. However, these amebae can also act as opportunistic as well as …

Opportunistic amoebae: challenges in prophylaxis and treatment

FL Schuster, GS Visvesvara - Drug Resistance Updates, 2004 - Elsevier
This review focuses on free-living amoebae, widely distributed in soil and water, causing
opportunistic and non-opportunistic infections in humans: Acanthamoeba spp., Balamuthia …

CYP51 as drug targets for fungi and protozoan parasites: past, present and future

GI Lepesheva, L Friggeri, MR Waterman - Parasitology, 2018 - cambridge.org
The efficiency of treatment of human infections with the unicellular eukaryotic pathogens
such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates …

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae

CA Rice, BL Colon, E Chen, MV Hull… - PLoS Neglected …, 2020 - journals.plos.org
Diseases caused by pathogenic free-living amoebae include primary amoebic
meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis …

Importance of nonenteric protozoan infections in immunocompromised people

JLN Barratt, J Harkness, D Marriott… - Clinical microbiology …, 2010 - Am Soc Microbiol
There are many neglected nonenteric protozoa able to cause serious morbidity and mortality
in humans, particularly in the developing world. Diseases caused by certain protozoa are …

Paradigms of Protist/Bacteria Symbioses Affecting Human Health: Acanthamoeba species and Trichomonas vaginalis

FL Henriquez, R Mooney, T Bandel… - Frontiers in …, 2021 - frontiersin.org
Ever since the publication of the seminal paper by Lynn Margulis in 1967 proposing the
theory of the endosymbiotic origin of organelles, the study of the symbiotic relationships …

Successful treatment of Acanthamoeba meningitis with combination oral antimicrobials

T Singhal, A Bajpai, V Kalra, SK Kabra… - The Pediatric …, 2001 - journals.lww.com
Acanthamoeba was implicated as the causative agent of chronic meningitis in three
apparently immunocompetent children. Diagnosis was established by cerebrospinal fluid …

Disseminated acanthamebiasis in a renal transplant recipient with osteomyelitis and cutaneous lesions: case report and literature review

JP Steinberg, RL Galindo, ES Kraus… - Clinical Infectious …, 2002 - academic.oup.com
Disseminated acanthamebiasis is a rare disease that occurs predominantly in patients with
human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome but …

Parasitic infections in transplant recipients

RS Barsoum - Nature Clinical Practice Nephrology, 2006 - nature.com
Parasitic infections are important complications of organ transplantation that are often
overlooked in the differential diagnosis of post-transplantation pyrexial illness. Although their …

Solid organ transplant and parasitic diseases: a review of the clinical cases in the last two decades

S Fabiani, S Fortunato, F Bruschi - Pathogens, 2018 - mdpi.com
The aim of this study was to evaluate the occurrence of parasitic infections in solid organ
transplant (SOT) recipients. We conducted a systematic review of literature records on post …