Neuronal wiring diagram of an adult brain

S Dorkenwald, A Matsliah, AR Sterling, P Schlegel… - Nature, 2024 - nature.com
Connections between neurons can be mapped by acquiring and analysing electron
microscopic brain images. In recent years, this approach has been applied to chunks of …

[HTML][HTML] Building and integrating brain-wide maps of nervous system function in invertebrates

TS Kramer, SW Flavell - Current Opinion in Neurobiology, 2024 - Elsevier
The selection and execution of context-appropriate behaviors is controlled by the integrated
action of neural circuits throughout the brain. However, how activity is coordinated across …

Connectome-constrained networks predict neural activity across the fly visual system

JK Lappalainen, FD Tschopp, S Prakhya, M McGill… - Nature, 2024 - nature.com
We can now measure the connectivity of every neuron in a neural circuit,,,,,,,–, but we cannot
measure other biological details, including the dynamical characteristics of each neuron …

[HTML][HTML] Network statistics of the whole-brain connectome of Drosophila

A Lin, R Yang, S Dorkenwald, A Matsliah, AR Sterling… - Nature, 2024 - nature.com
Brains comprise complex networks of neurons and connections, similar to the nodes and
edges of artificial networks. Network analysis applied to the wiring diagrams of brains can …

Connectomic reconstruction of a female Drosophila ventral nerve cord

A Azevedo, E Lesser, JS Phelps, B Mark, L Elabbady… - Nature, 2024 - nature.com
A deep understanding of how the brain controls behaviour requires mapping neural circuits
down to the muscles that they control. Here, we apply automated tools to segment neurons …

Descending control of motor sequences in Drosophila

JH Simpson - Current Opinion in Neurobiology, 2024 - Elsevier
The descending neurons connecting the fly's brain to its ventral nerve cord respond to
sensory stimuli and evoke motor programs of varying complexity. Anatomical …

A Drosophila computational brain model reveals sensorimotor processing

PK Shiu, GR Sterne, N Spiller, R Franconville… - Nature, 2024 - nature.com
The recent assembly of the adult Drosophila melanogaster central brain connectome,
containing more than 125,000 neurons and 50 million synaptic connections, provides a …

Neuronal parts list and wiring diagram for a visual system

A Matsliah, S Yu, K Kruk, D Bland, AT Burke, J Gager… - Nature, 2024 - nature.com
A catalogue of neuronal cell types has often been called a 'parts list'of the brain, and
regarded as a prerequisite for understanding brain function,. In the optic lobe of Drosophila …

Predicting visual function by interpreting a neuronal wiring diagram

HS Seung - Nature, 2024 - nature.com
As connectomics advances, it will become commonplace to know far more about the
structure of a nervous system than about its function. The starting point for many …

Synaptic connectome of the Drosophila circadian clock

N Reinhard, A Fukuda, G Manoli, E Derksen… - Nature …, 2024 - nature.com
The circadian clock and its output pathways play a pivotal role in optimizing daily processes.
To obtain insights into how diverse rhythmic physiology and behaviors are orchestrated, we …