DNA methyltransferases: a novel target for prevention and therapy
Cancer is the second leading cause of death in US. Despite the emergence of new, targeted
agents, and the use of various therapeutic combinations, none of the available treatment …
agents, and the use of various therapeutic combinations, none of the available treatment …
Inhibition of the CCL5/CCR5 axis against the progression of gastric cancer
D Aldinucci, N Casagrande - International journal of molecular sciences, 2018 - mdpi.com
Despite the progress made in molecular and clinical research, patients with advanced-stage
gastric cancer (GC) have a bad prognosis and very low survival rates. Furthermore, it is …
gastric cancer (GC) have a bad prognosis and very low survival rates. Furthermore, it is …
miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression
H Tang, M Deng, Y Tang, X Xie, J Guo, Y Kong… - Clinical Cancer …, 2013 - AACR
Purpose: The purpose of this study was to investigate the clinicopathologic significance and
potential role of miR-200b and miR-200c in the development and progression of gastric …
potential role of miR-200b and miR-200c in the development and progression of gastric …
An isothermal autocatalytic hybridization reaction circuit for sensitive detection of DNA methyltransferase and inhibitors assay
F Li, Y Chen, J Shang, Q Wang, S He, X Xing… - Analytical …, 2022 - ACS Publications
Abnormal DNA methylation contributes to the annoying tumorigenesis and the elevated
expression of methylation-related methyltransferase (MTase) is associated with many …
expression of methylation-related methyltransferase (MTase) is associated with many …
DNA methyltransferase-1 inhibitors as epigenetic therapy for cancer
DNA methylation is an epigenetic modification involved in gene expression regulation. In
cancer, the DNA methylation pattern becomes aberrant, causing an array of tumor …
cancer, the DNA methylation pattern becomes aberrant, causing an array of tumor …
SMARCA4/BRG1 Is a Novel Prognostic Biomarker Predictive of Cisplatin-Based Chemotherapy Outcomes in Resected Non–Small Cell Lung Cancer
Purpose: Identification of predictive biomarkers is critically needed to improve selection of
patients who derive the most benefit from platinum-based chemotherapy. We hypothesized …
patients who derive the most benefit from platinum-based chemotherapy. We hypothesized …
Efficient enhancement of electrochemiluminescence from cadmium sulfide quantum dots by glucose oxidase mimicking gold nanoparticles for highly sensitive assay …
H Zhou, T Han, Q Wei, S Zhang - Analytical chemistry, 2016 - ACS Publications
Herein, an original electrochemiluminescence (ECL) method for the detection of DNA
methyltransferase (MTase) activity is presented based on the efficient enhanced ECL of CdS …
methyltransferase (MTase) activity is presented based on the efficient enhanced ECL of CdS …
A novel signal-off photoelectrochemical biosensor for M. SssI MTase activity assay based on GQDs@ ZIF-8 polyhedra as signal quencher
L Meng, K Xiao, X Zhang, C Du, J Chen - Biosensors and Bioelectronics, 2020 - Elsevier
DNA methylation catalyzed by M. SssI methyltransferases (MTase) has important roles in
gene expression and other cellular activities, and relates to some diseases, especially …
gene expression and other cellular activities, and relates to some diseases, especially …
Tumor-associated macrophages promote epigenetic silencing of gelsolin through DNA methyltransferase 1 in gastric cancer cells
HC Wang, CW Chen, CL Yang, IM Tsai, YC Hou… - Cancer immunology …, 2017 - AACR
Epigenetic repression of the tumor suppressor gelsolin (GSN) is frequently observed in
cancers. Chronic inflammation can promote tumor progression via aberrant DNA …
cancers. Chronic inflammation can promote tumor progression via aberrant DNA …
Coupling WO3− x dots-encapsulated metal-organic frameworks and template-free branched polymerization for dual signal-amplified electrochemiluminescence …
F Yin, E Yang, X Ge, Q Sun, F Mo, G Wu… - Chinese Chemical …, 2024 - Elsevier
Developing accurate and sensitive DNA methyltransferase (MTase) analysis methods is
essential for early clinical diagnosis and development of antimicrobial drug targets. In this …
essential for early clinical diagnosis and development of antimicrobial drug targets. In this …