Nanoparticles are promising vehicles for the precise delivery of molecular therapies to
diseased sites. Nanoparticles interact with a series of tissues and cells before they reach …

Nanotechnology brings hope for targeted drug delivery. However, most current drug delivery
systems used passive delivery strategies with limited therapeutic efficiency. Over the past …

Nanoparticles need to navigate a complex microenvironment to target cells in solid tumors
after extravasation. Diffusion is currently the accepted primary mechanism for nanoparticle …

Nanomedicines have been approved to treat multiple human diseases. However, clinical
adoption of nanoformulated agents is often hindered by concerns about hepatic uptake and …

Although direct hepatic stellate cell (HSC) inhibition is considered a promising strategy for
alleviating liver fibrosis, traditional therapies struggle with off‐target effects due to limited …

Tumor-associated macrophages (TAMs) have emerged as therapeutic interests in cancer
nanomedicine because TAMs play a pivotal role in the immune microenvironment of solid …

Nanoparticles interact with immune cells in many different ways. These interactions are
crucially important for determining nanoparticles' ability to be used for cancer therapy …

Nanoparticles are used as delivery platforms for cancer therapeutics or imaging agents to
tumours. However, the translation of nanoparticle therapy is hindered by the limited …