Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors

L Jia, N Han, J Du, L Guo, Z Luo, Y Liu - Frontiers in cellular and …, 2019 - frontiersin.org
Periodontitis is a common intraoral infection and is inextricably linked to systemic diseases.
Recently, the regulation between host immunologic response and periodontal pathogens …

[HTML][HTML] Immunomodulatory properties of dental tissue-derived mesenchymal stem cells: implication in disease and tissue regeneration

O Andrukhov, C Behm, A Blufstein… - World journal of stem …, 2019 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are considered as an attractive tool for tissue regeneration
and possess a strong immunomodulatory ability. Dental tissue-derived MSCs can be …

Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human

B Nativel, D Couret, P Giraud, O Meilhac… - Scientific Reports, 2017 - nature.com
Porphyromonas gingivalis is a key bacterium in chronic periodontitis, which is associated
with several chronic inflammatory diseases. Lipopolysaccharides from P. gingivalis (Pg LPS) …

The periodontal stem/progenitor cell inflammatory‐regenerative cross talk: A new perspective

KM Fawzy El‐Sayed, M Elahmady… - Journal of …, 2019 - Wiley Online Library
Adult multipotent stem/progenitor cells, with remarkable regenerative potential, have been
isolated from various components of the human periodontium. These multipotent …

Response of human mesenchymal stromal cells from periodontal tissue to LPS depends on the purity but not on the LPS source

C Behm, A Blufstein, SY Abhari, C Koch… - Mediators of …, 2020 - Wiley Online Library
Human periodontal ligament stromal cells (hPDLSCs) and gingival mesenchymal stromal
cells (hGMSCs) are resident mesenchymal stromal cells (MSCs) of the periodontal tissue …

Response of human periodontal ligament stem cells to IFN-γ and TLR-agonists

O Andrukhov, JSA Hong, O Andrukhova, A Blufstein… - Scientific Reports, 2017 - nature.com
Periodontal ligament stem cells similarly to the mesenchymal stem cells of other tissues
possess immunomodulatory properties, which are regulated by different cytokines …

Effect of implant surface material and roughness to the susceptibility of primary gingival fibroblasts to inflammatory stimuli

O Andrukhov, C Behm, A Blufstein, C Wehner, J Gahn… - Dental Materials, 2020 - Elsevier
Objectives The impact of the implant surface material and roughness on inflammatory
processes in peri-implantitis is not entirely clear. Hence, we investigated how titanium and …

Toll-like receptors and dental mesenchymal stromal cells

O Andrukhov - Frontiers in Oral Health, 2021 - frontiersin.org
Dental mesenchymal stromal cells (MSCs) are a promising tool for clinical application in and
beyond dentistry. These cells possess multilineage differentiation potential and …

[HTML][HTML] Red-complex bacteria exhibit distinctly different interactions with human periodontal ligament stromal cells compared to Fusobacterium nucleatum

FL Kendlbacher, S Bloch, FF Hager-Mair… - Archives of Oral …, 2024 - Elsevier
Objective The red-complex bacteria Porphyromonas gingivalis and Tannerella forsythia
together with Fusobacterium nucleatum are essential players in periodontitis. This study …

Cytokines differently define the immunomodulation of mesenchymal stem cells from the periodontal ligament

C Behm, A Blufstein, J Gahn, M Nemec, A Moritz… - Cells, 2020 - mdpi.com
Human periodontal ligament stem cells (hPDLSCs) play an important role in periodontal
tissue homeostasis and regeneration. The function of these cells in vivo depends largely on …