Background Recent studies have shown that the accumulation of free iron and lipid
peroxides will trigger a new form of cell death—ferroptosis. This form of cell death is …

Myelodysplastic syndromes are a heterogeneous group of bone marrow disorders
characterized by ineffective hematopoiesis, progressive cytopenias, and an innate capability …

Iron metabolism plays a crucial role in cell viability, but its relationship with adult stem cells
and cancer stem cells is not fully understood. The ferritin complex, responsible for …

Objective: To determine the prevalence of iron overload in children with acute lymphoblastic
leukemia (ALL) after treatment cessation and establish a cutoff value for serum ferritin level …

Iron overload is a common complication in patients with chronic renal failure treated with
dialysis prior to the availability of recombinant human erythropoietin therapy. Iron overload …

Background Adolescents and young adults diagnosed with acute lymphoblastic leukemia
are treated according to pediatric-based regimens to achieve better results. However …

system, increasing susceptibility to infections. Emerging evidence suggests that iron
overload in T-ALL patients may create an ideal environment for viral infections to thrive [5] …

Secondary iron overload is a common complication in the context of hematological
diseases, as iron accumulates due to different mechanisms including chronic transfusion …

Secondary iron overload is increasingly encountered in chronic kidney disease (CKD)
patients because of the frequent use of parenteral iron products, especially in hemodialysis …

Objective: There are a limited number of studies evaluating iron overload in childhood
leukemia by magnetic resonance imaging (MRI). The aim of this study was to determine liver …