The neurotransmitters GABA and glycine mediate fast synaptic inhibition by activating ligand-
gated chloride channels—namely, type A GABA (GABAA) and glycine receptors. Both types …

GABAA receptors (GABAAR s) are ligand‐gated Cl− channels that mediate most of the fast
inhibitory neurotransmission in the central nervous system (CNS). Multiple GABAAR …

Mutations disrupting the nuclear localization of the RNA-binding protein FUS characterize a
subset of amyotrophic lateral sclerosis patients (ALS-FUS). FUS regulates nuclear RNAs …

Repetitive transcranial magnetic stimulation (rTMS) is used as a therapeutic tool in
neurology and psychiatry. While repetitive magnetic stimulation (rMS) has been shown to …

Glycogen synthase kinase-3 (GSK-3) has many cellular functions. Recent evidence
suggests that it plays a key role in certain types of synaptic plasticity, in particular a form of …

Gephyrin is a central element that anchors, clusters and stabilizes glycine and γ-
aminobutyric acid type A receptors at inhibitory synapses of the mammalian brain. It self …

The potency of GABA is vitally important for its primary role in activating GABAA receptors
and acting as an inhibitory neurotransmitter. Although numerous laboratories have …

GABAA receptors (GABAAR) are the major players in fast inhibitory neurotransmission in the
central nervous system (CNS). Regulation of GABAAR trafficking and the control of their …

Epilepsy is a common neurological disorder associated with alterations of excitation‐
inhibition balance within brain neuronal networks. GABAA receptor neurotransmission is the …

Inhibitory synapses are also known as symmetric synapses due to their lack of prominent
postsynaptic densities (PSDs) under a conventional electron microscope (EM). Recent cryo …