Neuropeptide substance P and the immune response

A Mashaghi, A Marmalidou, M Tehrani… - Cellular and molecular …, 2016 - Springer
Substance P is a peptide mainly secreted by neurons and is involved in many biological
processes, including nociception and inflammation. Animal models have provided insights …

Th17 cells pathways in multiple sclerosis and neuromyelitis optica spectrum disorders: pathophysiological and therapeutic implications

GRD Passos, DK Sato, J Becker… - Mediators of …, 2016 - Wiley Online Library
Several animal and human studies have implicated CD4+ T helper 17 (Th17) cells and their
downstream pathways in the pathogenesis of central nervous system (CNS) autoimmunity in …

The role of interleukin (IL)‐17 in anxiety and depression of patients with rheumatoid arthritis

Y Liu, RCM HO, A Mak - International journal of rheumatic …, 2012 - Wiley Online Library
Background: Pro‐inflammatory cytokines are found to be elevated in patients with anxiety
and depression but whether their serum levels are related to anxiety and depression is …

The role of nociceptive neurons in the pathogenesis of psoriasis

X Zhang, Y He - Frontiers in Immunology, 2020 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease. Emerging evidence shows that neurogenic
inflammation, induced by nociceptive neurons and T helper 17 cell (Th17) responses, has a …

A neuroimmunological perspective on anxiety disorders

R Hou, DS Baldwin - Human Psychopharmacology: Clinical …, 2012 - Wiley Online Library
Objective Research into psychoneuroimmunology has led to substantial advances in our
understanding of the reciprocal interactions between the central nervous system and the …

Role of neuroendocrine and neuroimmune mechanisms in chronic inflammatory rheumatic diseases—the 10-year update

RH Straub, JWJ Bijlsma, A Masi, M Cutolo - Seminars in arthritis and …, 2013 - Elsevier
Background Neuroendocrine immunology in musculoskeletal diseases is an emerging
scientific field. It deals with the aspects of efferent neuronal and neurohormonal bearing on …

The role of Th17 cells in the pathophysiology of pregnancy and perinatal mood and anxiety disorders

LM Osborne, A Brar, SL Klein - Brain, behavior, and immunity, 2019 - Elsevier
T cells play a key role in adaptive immune responses, and shifts among T cell classes occur
in normal pregnancy. There is evidence for the role of TH 17 cells and dysregulation of the …

[HTML][HTML] Treatment response biomarkers in anxiety disorders: From neuroimaging to neuronally-derived extracellular vesicles and beyond

JR Strawn, A Levine - Biomarkers in neuropsychiatry, 2020 - Elsevier
Multiple and diverse psychotherapeutic or psychopharmacologic treatments effectively
reduce symptoms for many patients with anxiety disorders, but the trajectory and magnitude …

Interleukin‐17/T‐helper 17 cells in an atopic dermatitis mouse model aggravate orthodontic root resorption in dental pulp

M Shimizu, M Yamaguchi, S Fujita… - European Journal of …, 2013 - Wiley Online Library
Interleukin (IL)‐17 is an important mediator of orthodontically induced inflammatory root
resorption (OIIRR). However, its role in the dental pulp (DP) has not been studied. The aim …

Neuropeptides as therapeutic targets to combat stress-associated behavioral and neuroendocrinological effects

A Bali, N Singh, A Singh Jaggi - CNS & Neurological Disorders …, 2014 - ingentaconnect.com
Stress has become an integral part of human life and organisms are being constantly
subjected to stress and the ability to cope with such stress is a crucial determinant of health …