Paclitaxel is a broad‐spectrum anticancer compound, which was derived mainly from a
medicinal plant, in particular, from the bark of the yew tree Taxus brevifolia Nutt. It is a …

Paclitaxel is a well-known anticancer agent with a unique mechanism of action. It is
considered to be one of the most successful natural anticancer drugs available. This study …

Paclitaxel (PTX) is an effective anticancer chemical with a broad spectrum that was primarily
obtained from a curative shrub, specifically the bark of Taxus brevifolia tree. It belongs to a …

Epidermal growth factor receptor (EGFR) plays a key role in signal transduction pathways
associated with cell proliferation, growth, and survival. Its overexpression and aberrant …

The nano drug delivery system (NDDS) has been extensively investigated for cancer
treatment because of its ability to enhance drug efficacy. However, there are only a few …

The pharmacoepigenetic apparatus is integrated by gene clusters of different categories,
including (i) pathogenic genes involved in disease pathogenesis,(ii) mechanistic genes …

Paclitaxel (PTX) is a broad‐spectrum alkaloid anticancer drug with high therapeutic efficacy.
However, PTX has a very low water solubility and its metabolism demonstrates nonlinear …

Research has recently focused on combinational therapy using nanocarriers to overcome
the obstacles associated with conventional therapy of lung cancer. The classical therapeutic …

Microtubules are dynamic proteins that play crucial roles in the normal functions of cells.
Chromosome missegregation driven by microtubules during cell division can lead to several …

Our previous studies reported that low-dose paclitaxel (Taxol) ameliorated renal fibrosis in
the unilateral ureteral obstruction and remnant kidney models. However, the regulatory role …