G Desmet, K Broeckhoven - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Columns for liquid chromatography produce ever narrower peaks and analysts continue to push to smaller column diameters to save solvents and have better MS responses. The …
MB Tennikov, NV Gazdina, TB Tennikova… - … of Chromatography A, 1998 - Elsevier
The effect of porous structures of 2-mm thick diethylamine functionalized monolithic polymethacrylate discs on their chromatographic behavior in ion-exchange mode has been …
CR Bernau, M Knödler, J Emonts, RC Jäpel… - … in Bioengineering and …, 2022 - frontiersin.org
Chromatography is the workhorse of biopharmaceutical downstream processing because it can selectively enrich a target product while removing impurities from complex feed streams …
MA Teeters, SE Conrardy, BL Thomas, TW Root… - … of Chromatography A, 2003 - Elsevier
Adsorptive membranes were investigated for the downstream processing of plasmid DNA by quantifying both separation efficiencies and adsorption uptake with the anion-exchange …
F Hagemann, D Wypysek, K Baitalow… - Journal of …, 2022 - Elsevier
In preparative chromatography, a uniform flow distribution through the chromatography device is essential to get an effective ligand utilization and a breakthrough curve that is as …
F Gritti - Journal of Chromatography A, 2023 - Elsevier
The flow reversal (FR) technique consists of reversing the flow direction along a chromatographic column. It is used to reveal the origin (such as poor column packing, active …
M Barut, A Podgornik, P Brne… - Journal of separation …, 2005 - Wiley Online Library
New therapeutics that are being developed rely more and more on large and complex biomacromolecules like proteins, DNA, and viral particles. Manufacturing processes are …
Molecularly imprinted polymer membranes for a model compound, atrazine, were prepared in situ from a monomer mixture containing methacrylic acid, tri (ethylene glycol) …
QS Yuan, A Rosenfeld, TW Root… - … of Chromatography A, 1999 - Elsevier
It becomes increasingly clear that flow non-uniformity frequently limits the performance of chromatographic columns, and that there are at least two major causes for this: non-uniform …