SARS-CoV-2 is a novel β-coronavirus that caused the COVID-19 pandemic disease, which
spread rapidly, infecting more than 134 million people, and killing almost 2.9 million thus far …

Monoclonal therapeutic antibodies have revolutionized the treatment of cancer and other
diseases. Fc engineering aims to enhance the effector functions or half-life of therapeutic …

Human epidermal growth factor receptor 2 (HER2) is a receptor tyrosine kinase that plays an
oncogenic role in breast, gastric and other solid tumors. However, anti-HER2 therapies are …

Antibody-drug conjugates (ADCs) provide effective cancer treatment through the selective
delivery of cytotoxic payloads to the cancer cells. They offer unparalleled precision and …

While chemotherapy and radiotherapy remain the first-line approaches for the management
of most unresectable tumors, immunotherapy has emerged in the past two decades as a …

Correlates of protection (CoP) are biological parameters that predict a certain level of
protection against an infectious disease. Well-established correlates of protection facilitate …

Background Edible swiftlet's nest (ESN) is dried gelatinized saliva secreted by swiftlets
during the breeding season. The ESN has been widely consumed as a food and medicine …

Monoclonal antibodies directed against the CD20 surface antigen on B cells are widely
used in the therapy of B cell malignancies. Upon administration, the antibodies bind to CD20 …

T cell engagers, a category of T cell-retargeting immunotherapy, are rapidly transforming
clinical cancer care. However, the lack of tumor-specific targets poses a significant …

Background Colorectal cancer (CRC) is highly prevalent and lethal globally, and its
prognosis remains unsatisfactory. Drug resistance is regarded as the main cause of …