Association of metabolic and inflammatory markers with polycystic ovarian syndrome (PCOS): an update

S Abraham Gnanadass, Y Divakar Prabhu… - Archives of Gynecology …, 2021 - Springer
Background Polycystic ovarian syndrome (PCOS) is the most prevalent metabolic disorder
in reproductive-age women. It is indeed a multifactorial condition evidenced by ovarian …

Molecular signatures of obstructive sleep apnea in adults: a review and perspective

ES Arnardottir, M Mackiewicz, T Gislason, KL Teff… - Sleep, 2009 - academic.oup.com
The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

M Feuerer, L Herrero, D Cipolletta, A Naaz, J Wong… - Nature medicine, 2009 - nature.com
Obesity is accompanied by chronic, low-grade inflammation of adipose tissue, which
promotes insulin resistance and type-2 diabetes. These findings raise the question of how …

[HTML][HTML] Obesity induces a phenotypic switch in adipose tissue macrophage polarization

CN Lumeng, JL Bodzin, AR Saltiel - The Journal of clinical …, 2007 - Am Soc Clin Investig
Monocytes participate critically in atherosclerosis. There are 2 major subsets expressing
different chemokine receptor patterns: CCR2+ CX3CR1+ Ly-6Chi and CCR2–CX3CR1++ …

Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle

EG Hong, HJ Ko, YR Cho, HJ Kim, Z Ma, TY Yu… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Insulin resistance is a major characteristic of type 2 diabetes and is causally
associated with obesity. Inflammation plays an important role in obesity-associated insulin …

[HTML][HTML] IL-6, TNF-α, and IL-10 levels/polymorphisms and their association with type 2 diabetes mellitus and obesity in Brazilian individuals

KF Rodrigues, NT Pietrani, AA Bosco… - … of endocrinology and …, 2017 - SciELO Brasil
Objective This study aimed to investigate the association of plasma TNF-α, IL-6, and lL-10
levels and cytokine gene polymorphisms [TNF-α (-308 G→ A), IL-6 (-174 C→ G) and IL-10 …

IL-10 as a Th2 cytokine: differences between mice and humans

MT Rasquinha, M Sur, N Lasrado… - The Journal of …, 2021 - journals.aai.org
The discovery of IL-10 more than 30 years ago marked the beginning of our understanding
of how cytokines regulate immune responses, based on cross-regulation between Th1 and …

Effects of 12 weeks high dose vitamin D3 treatment on insulin sensitivity, beta cell function, and metabolic markers in patients with type 2 diabetes and vitamin D …

U Kampmann, L Mosekilde, C Juhl, N Moller… - Metabolism, 2014 - Elsevier
Objectives Vitamin D insufficiency is common in subjects with type 2 diabetes. Observational
studies suggest that vitamin D plays a role in the pathogenesis of type 2 diabetes. However …

Adipose tissue immunity and cancer

V Catalán, J Gómez-Ambrosi, A Rodríguez… - Frontiers in …, 2013 - frontiersin.org
Inflammation and altered immune response are important components of obesity and
contribute greatly to the promotion of obesity-related metabolic complications, especially …

Interpreting 'anti‐inflammatory'cytokine responses to exercise: focus on interleukin‐10

H Islam, H Neudorf, AL Mui… - The Journal of …, 2021 - Wiley Online Library
Circulating concentrations of canonically pro‐and anti‐inflammatory cytokines are
commonly measured when evaluating the anti‐inflammatory effects of exercise. An …