Blue-light receptors for optogenetics

A Losi, KH Gardner, A Möglich - Chemical reviews, 2018 - ACS Publications
Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …

Seeing (and using) the light: recent developments in bioluminescence technology

AC Love, JA Prescher - Cell Chemical Biology, 2020 - cell.com
Bioluminescence has long been used to image biological processes in vivo. This technology
features luciferase enzymes and luciferin small molecules that produce visible light …

Reversible photoregulation of cell-cell adhesions with opto-E-cadherin

B Nzigou Mombo, BM Bijonowski, CA Raab… - Nature …, 2023 - nature.com
E-cadherin-based cell-cell adhesions are dynamically and locally regulated in many
essential processes, including embryogenesis, wound healing and tissue organization, with …

Optogenetics for transcriptional programming and genetic engineering

TH Lan, L He, Y Huang, Y Zhou - Trends in Genetics, 2022 - cell.com
Optogenetics combines genetics and biophotonics to enable noninvasive control of
biological processes with high spatiotemporal precision. When engineered into protein …

[HTML][HTML] How light affects the life of Botrytis

J Schumacher - Fungal Genetics and Biology, 2017 - Elsevier
Fungi, like other organisms, actively sense the environmental light conditions in order to
drive adaptive responses, including protective mechanisms against the light-associated …

Illuminating the inner workings of a natural protein switch: Blue-light sensing in LOV-activated diguanylate cyclases

U Vide, D Kasapović, M Fuchs, MP Heimböck… - Science …, 2023 - science.org
Regulatory proteins play a crucial role in adaptation to environmental cues. Especially for
lifestyle transitions, such as cell proliferation or apoptosis, switch-like characteristics are …

Engineering AraC to make it responsive to light instead of arabinose

E Romano, A Baumschlager, EB Akmeric… - Nature chemical …, 2021 - nature.com
The l-arabinose-responsive AraC and its cognate PBAD promoter underlie one of the most
often used chemically inducible prokaryotic gene expression systems in microbiology and …

Principles and applications of optogenetics in developmental biology

D Krueger, E Izquierdo, R Viswanathan… - …, 2019 - journals.biologists.com
The development of multicellular organisms is controlled by highly dynamic molecular and
cellular processes organized in spatially restricted patterns. Recent advances in …

[HTML][HTML] Chromosome-level genomes of multicellular algal sisters to land plants illuminate signaling network evolution

X Feng, J Zheng, I Irisarri, H Yu, B Zheng, Z Ali… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The filamentous and unicellular algae of the class Zygnematophyceae are the closest algal
relatives of land plants. Inferring the properties of the last common ancestor shared by these …

Spatiotemporal compartmentalization of hepatic NADH and NADPH metabolism

RP Goodman, SE Calvo, VK Mootha - Journal of Biological Chemistry, 2018 - ASBMB
Compartmentalization is a fundamental design principle of eukaryotic metabolism. Here, we
review the compartmentalization of NAD+/NADH and NADP+/NADPH with a focus on the …