Neurochemical and molecular mechanisms underlying the retrieval-extinction effect

EN Cahill, AL Milton - Psychopharmacology, 2019 - Springer
Extinction within the reconsolidation window, or 'retrieval-extinction', has received much
research interest as a possible technique for targeting the reconsolidation of maladaptive …

ProBDNF dependence of LTD and fear extinction learning in the amygdala of adult mice

X Ma, H Vuyyuru, T Munsch, T Endres… - Cerebral …, 2022 - academic.oup.com
Neurotrophins are secreted proteins that control survival, differentiation, and synaptic
plasticity. While mature neurotrophins regulate these functions via tyrosine kinase signaling …

Acute food deprivation enhances fear extinction but inhibits long-term depression in the lateral amygdala via ghrelin signaling

CC Huang, D Chou, CM Yeh, KS Hsu - Neuropharmacology, 2016 - Elsevier
Fear memory-encoding thalamic input synapses to the lateral amygdala (T-LA) exhibit
dynamic efficacy changes that are tightly correlated with fear memory strength. Previous …

Selective Antagonism of mGluR5 Alters Sleep-Wake and Quantitative EEG and Ameliorates Behavioral Abnormalities in a Rodent Model of Traumatic Stress

MT Nedelcovych - 2015 - ir.vanderbilt.edu
Post-Traumatic Stress Disorder (PTSD) is characterized by persistent stress responses after
experiencing a traumatic event. Hyperarousal and accompanying sleep disruptions, such as …