[HTML][HTML] Coagulopathy in COVID‐19

T Iba, JH Levy, M Levi, J Thachil - Journal of thrombosis and haemostasis, 2020 - Elsevier
The COVID‐19 pandemic has become an urgent issue in every country. Based on recent
reports, the most severely ill patients present with coagulopathy, and disseminated …

Ebola virus disease

ST Jacob, I Crozier, WA Fischer, A Hewlett… - Nature reviews Disease …, 2020 - nature.com
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

D Mathew, JR Giles, AE Baxter, DA Oldridge… - Science, 2020 - science.org
INTRODUCTION Many patients with coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, present with …

[HTML][HTML] Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

I Thevarajan, THO Nguyen, M Koutsakos, J Druce… - Nature medicine, 2020 - nature.com
To the Editor—We report the kinetics of immune responses in relation to clinical and
virological features of a patient with mild-to-moderate coronavirus disease 2019 (COVID-19) …

Comprehensive mapping of immune perturbations associated with severe COVID-19

L Kuri-Cervantes, MB Pampena, W Meng… - Science …, 2020 - science.org
Although critical illness has been associated with SARS-CoV-2–induced hyperinflammation,
the immune correlates of severe COVID-19 remain unclear. Here, we comprehensively …

Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19

LA Vella, JR Giles, AE Baxter, DA Oldridge… - Science …, 2021 - science.org
Pediatric coronavirus disease 2019 (COVID-19) after SARS-CoV-2 infection is associated
with fewer hospitalizations and often milder disease than in adults. A subset of children …

Potential use of exosomes as diagnostic biomarkers and in targeted drug delivery: progress in clinical and preclinical applications

MN Huda, M Nafiujjaman, IG Deaguero… - ACS biomaterials …, 2021 - ACS Publications
Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …

Uncontrolled innate and impaired adaptive immune responses in patients with COVID-19 acute respiratory distress syndrome

S Hue, A Beldi-Ferchiou, I Bendib… - American journal of …, 2020 - atsjournals.org
Rationale: Uncontrolled inflammatory innate response and impaired adaptive immune
response are associated with clinical severity in patients with coronavirus disease (COVID …

Antibody and B cell responses to SARS-CoV-2 infection and vaccination

K Röltgen, SD Boyd - Cell host & microbe, 2021 - cell.com
Antibodies, and the B cell and plasma cell populations responsible for their production, are
key components of the human immune system's response to SARS-CoV-2, which has …

Remembrance of things past: long-term B cell memory after infection and vaccination

AKE Palm, C Henry - Frontiers in immunology, 2019 - frontiersin.org
The success of vaccines is dependent on the generation and maintenance of immunological
memory. The immune system can remember previously encountered pathogens, and …