Cumulative exposure to phthalates and their alternatives and associated female reproductive health: body burdens, adverse outcomes, and underlying mechanisms

X Weng, Q Zhu, C Liao, G Jiang - Environmental Science & …, 2023 - ACS Publications
The global birth rate has recently shown a decreasing trend, and exposure to environmental
pollutants has been identified as a potential factor affecting female reproductive health …

Nuclear Receptors-Mediated Endocrine Disrupting Effects of Non-Phthalate Plasticizers: A Review

J Yu, H Zou, T Zhang, J Zhang - Journal of Agricultural and Food …, 2023 - ACS Publications
In 2021, the global market for non-phthalate plasticizers reached $3.1 billion, and it is
projected to grow by 25.8% by 2025. These plasticizers have gained substantial attention as …

The relationship between phthalates and diabetes: a review

M Mariana, E Cairrao - Metabolites, 2023 - mdpi.com
Since the beginning of their production, in the 1930s, phthalates have been widely used in
the plastics industry to provide durability and elasticity to polymers that would otherwise be …

[HTML][HTML] Structural basis of the activation of PPARγ by the plasticizer metabolites MEHP and MINCH

A Useini, F Engelberger, G Künze, N Sträter - Environment International, 2023 - Elsevier
Abstract Di-2-ethylhexyl phthalate (DEHP) and its substitute 1, 2-cyclohexane dicarboxylic
acid diisononyl ester (DINCH) are widely used as plasticizers but may have adverse health …

[HTML][HTML] Phthalate exposure and the metabolic syndrome: A systematic review and meta-analysis

DM Merida, B Moreno-Franco, M Marques… - Environmental …, 2023 - Elsevier
Phthalates are chemicals widely used in plastic-based consumer products, and human
exposure is universal. They are classified as endocrine disruptors, and specific phthalate …

Global environmental and toxicological data of emerging plasticizers: current knowledge, regrettable substitution dilemma, green solution and future perspectives

A Qadeer, M Anis, GR Warner, C Potts… - Green …, 2024 - pubs.rsc.org
The global plasticizer market is projected to increase from $17 billion in 2022 to $22.5 billion
in 2027. Various emerging/alternative plasticizers entered the market following the ban on …

The role of endocrine disruptors bisphenols and phthalates in obesity: current evidence, perspectives and controversies

M Dalamaga, D Kounatidis, D Tsilingiris… - International Journal of …, 2024 - mdpi.com
Excess body weight constitutes one of the major health challenges for societies and
healthcare systems worldwide. Besides the type of diet, calorie intake and the lack of …

Early pregnancy phthalates and replacements in relation to fetal growth: The human placenta and phthalates study

DR Stevens, EM Rosen, K Van Wickle, EE McNell… - Environmental …, 2023 - Elsevier
Background Pregnant persons are exposed ubiquitously to phthalates and increasingly to
chemicals introduced to replace phthalates. In early pregnancy, exposure to these …

Worsening of imiquimod-induced psoriasiform inflammation in mice by environmental pollutant, di-(2-ethylhexyl) phthalate through dysregulation in IL-17A and Nrf2 …

AS Alfardan, A Nadeem, SF Ahmad, NO Al-Harbi… - International …, 2024 - Elsevier
Psoriasis is a devastating autoimmune illness resulting from excessive keratinocyte growth
and leukocyte infiltration into the dermis/epidermis. In the pathogenesis of psoriasis, different …

[HTML][HTML] Maternal pre-pregnancy BMI influences the associations between bisphenol and phthalate exposures and maternal weight changes and fat accumulation

N Irvine, RC Bell, FB Subhan, CJ Field, J Liu… - Environmental …, 2024 - Elsevier
Background Bisphenols and phthalates are two classes of endocrine-disrupting chemicals
(EDCs) thought to influence weight and adiposity. Limited research has investigated their …