Diabetes and hypertension: is there a common metabolic pathway?

BMY Cheung, C Li - Current atherosclerosis reports, 2012 - Springer
Diabetes and hypertension frequently occur together. There is substantial overlap between
diabetes and hypertension in etiology and disease mechanisms. Obesity, inflammation …

Genetics of metabolic syndrome

A Stančáková, M Laakso - Reviews in Endocrine and Metabolic Disorders, 2014 - Springer
Metabolic syndrome (MetS) is a cluster of metabolic traits associated with an increased risk
of cardiovascular disease and type 2 diabetes mellitus. Central obesity and insulin …

[HTML][HTML] High dietary saturated fat intake accentuates obesity risk associated with the fat mass and obesity-associated gene in adults

CM Phillips, E Kesse-Guyot, R McManus… - The Journal of …, 2012 - Elsevier
Background: Fat mass and obesity-associated (FTO) is the strongest genetic determinant of
obesity identified to date. Dietary fat is a key environmental factor that may interact with …

Common genetic variation in obesity, lipid transfer genes and risk of Metabolic Syndrome: Results from IDEFICS/I. Family study and meta-analysis

R Nagrani, R Foraita, F Gianfagna, L Iacoviello… - Scientific reports, 2020 - nature.com
As the prevalence of metabolic syndrome (MetS) in children and young adults is increasing,
a better understanding of genetics that underlie MetS will provide critical insights into the …

The association of type 2 diabetes loci identified in genome-wide association studies with metabolic syndrome and its components in a Chinese population with type 2 …

X Kong, X Zhang, X Xing, B Zhang, J Hong, W Yang - PloS one, 2015 - journals.plos.org
Metabolic syndrome (MetS) is prevalent in type 2 diabetes (T2D) patients. The comorbidity of
MetS and T2D increases the risk of cardiovascular complications. The aim of the present …

Genetic variants in FTO associated with metabolic syndrome: a meta- and gene-based analysis

H Wang, S Dong, H Xu, J Qian, J Yang - Molecular biology reports, 2012 - Springer
The objective of this study was to examine the effect of genetic variants in fat mass and
obesity associated (FTO) gene on metabolic syndrome (MetS). A systematic literature search …

The (FTO) gene polymorphism is associated with metabolic syndrome risk in Egyptian females: a case- control study

MS Khella, NM Hamdy, AI Amin… - BMC medical genetics, 2017 - Springer
Background Variations within fat mass and obesity associated (FTO) gene had crosstalk with
obesity risk in European and some Asian populations. This study was designed to …

A haplotype of three SNPs in FTO had a strong association with body composition and BMI in Iranian male adolescents

N Kalantari, N Keshavarz Mohammadi, P Izadi… - PLoS …, 2018 - journals.plos.org
Background Single-nucleotide polymorphisms (SNPs), which are located in the first intron of
the FTO gene, are reported to be associated with body weight and the body mass index …

Common variant (rs9939609) in the FTO gene is associated with metabolic syndrome

D Zhou, H Liu, M Zhou, S Wang, J Zhang, L Liao… - Molecular biology …, 2012 - Springer
Recent genome-wide association studies have showed that common variant (rs9939609) in
fat mass and obesity associated (FTO) gene was significantly associated with type 2 …

A nutrigenetic approach to investigate the relationship between metabolic traits and vitamin D status in an Asian Indian population

BE Alathari, D Bodhini, R Jayashri, N Lakshmipriya… - Nutrients, 2020 - mdpi.com
Studies in Asian Indians have examined the association of metabolic traits with vitamin D
status. However, findings have been quite inconsistent. Hence, we aimed to explore the …