Protein kinase R (PKR)-like endoplasmic reticulum (ER) kinase (PERK) is one of the three
major sensors in the unfolded protein response (UPR). The UPR is involved in the …

Background Immunogenic cell death (ICD) is a form of cell death that elicits immune
responses against the antigens found in dead or dying tumor cells. Growing evidence …

Background The role of the unfolded protein response (UPR) has been progressively
unveiled over the last decade and several studies have investigated its implication in …

Stiffening of the brain extracellular matrix (ECM) in glioblastoma promotes tumor
progression. Previously, we discovered that protein kinase R (PKR)‐like endoplasmic …

GHRH regulates the secretion of GH from the anterior pituitary gland, previously associated
with cancer progression and inflammation. An emerging body of evidence suggests that …

Abstract Background Marinesco-Sjögren syndrome (MSS) is an autosomal recessive
neuromuscular disorder that arises in early childhood and is characterized by congenital …

Background: Medulloblastomas (MDB) are malignant, aggressive brain tumors that primarily
affect children. The survival rate for children under 14 is approximately 72%, while for ages …

Glioblastoma (GB) is the most common and aggressive form of primary malignant tumors in
the central nervous system. The prognosis of GB patients is generally poor, on average …

Glioblastoma multiforme (GBM) is an aggressive brain tumor, with no specific early
symptoms or apparent cause, for which there is currently no effective prevention or …