Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Indirubin is the crucial ingredient of Danggui Longhui Wan and Qing-Dai, traditional
Chinese medicine herbal formulas used for the therapy of chronic myelocytic leukemia in …

TCM-based medications have been used for millennia in China and have always been
“different” from current Western-based medicines in that they frequently are still mixtures of …

In this study, we report the combination of indirubin-3-monoxime (I3M) and thymoquinone
(Tq) to have excellent therapeutic efficacy in models of Lung cancer (LC). Preliminary …

Background The method of multiple targets overall control is increasingly used to predict the
main active ingredient and potential target group of Chinese traditional medicines and to …

The present review explores the critical role of oxime and oxime ether moieties in enhancing
the physicochemical and anticancer properties of structurally diverse molecular frameworks …

Rational combination of natural and synthetic derivatives to treat lung cancer has
advantages of both efficacy and safety. Herein, the combination of indirubin‐3‐monoxime …

Background: This research intended to predict the active ingredients and key target genes of
Indigo Naturalis in treating human chronic myeloid leukemia (CML) using network …

Qingdai, a traditional Chinese medicine (TCM) used for the treatment of chronic myeloid
leukemia (CML) with good efficacy, has been used in China for decades. However, due to …

Ethnopharmacological relevance Ancient mediterranean diet was characterized by
consuming the spontaneous forms of Cynara cardunculus L.(CCL), commonly called …