TRiC/CCT chaperonin: structure and function

M Jin, C Liu, W Han, Y Cong - Macromolecular Protein Complexes II …, 2019 - Springer
The eukaryotic group II chaperonin TRiC/CCT assists the folding of 10% of cytosolic proteins
including many key structural and regulatory proteins. TRiC plays an essential role in …

Negative epistasis in experimental RNA fitness landscapes

DP Bendixsen, B Østman, EJ Hayden - Journal of molecular evolution, 2017 - Springer
Mutations and their effects on fitness are a fundamental component of evolution. The effects
of some mutations change in the presence of other mutations, and this is referred to as …

Impact of genome reduction in microsporidia

N Jespersen, L Monrroy, J Barandun - Microsporidia: Current Advances in …, 2022 - Springer
Microsporidia represent an evolutionary outlier in the tree of life and occupy the extreme
edge of the eukaryotic domain with some of their biological features. Many of these …

Genetics animates structure: leveraging genetic interactions to study the dynamics of ribosome biogenesis

JJ Black, AW Johnson - Current Genetics, 2021 - Springer
The assembly of eukaryotic ribosomes follows an assembly line-like pathway in which
numerous trans-acting biogenesis factors act on discrete pre-ribosomal intermediates to …

Nucleolar protein treacle is important for the efficient growth of mumps virus

A Wakata, H Katoh, F Kato, M Takeda - Journal of Virology, 2022 - Am Soc Microbiol
The nucleolus is the largest structure in the nucleus, and it plays roles in mediating cellular
stress responses and regulating cell proliferation, as well as in ribosome biosynthesis. The …

Small changes, unexpected consequences: Molecular insights into substrate-dependent adaptation of KsgA/Dim1-dependent ribosomal RNA modifications in …

RM Knüppel - 2021 - epub.uni-regensburg.de
Classically, life is divided into three phylogenetically interconnected groups of organisms,
the archaea, bacteria and eukarya. However, they all share a central and universally …

[PDF][PDF] Small changes, unexpected consequences

RM Knüppel - core.ac.uk
Classically, life is divided into three phylogenetically interconnected groups of organisms,
the archaea, bacteria and eukarya. However, they all share a central and universally …

Transcriptome-Wide Mapping of Protein–RNA Interactions

X Bi, X Shen - RNA-Chromatin Interactions: Methods and Protocols, 2020 - Springer
RNA and RNA-binding proteins (RBPs) control multiple biological processes. The spatial
and temporal arrangement of RNAs and RBPs underlies the delicate regulation of these …