Hidradenitis suppurativa

R Sabat, GBE Jemec, Ł Matusiak, AB Kimball… - Nature Reviews …, 2020 - nature.com
Hidradenitis suppurativa (HS; also designated as acne inversa) is a chronic inflammatory
disorder, which affects the intertriginous skin and is associated with numerous systemic …

Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life

TV Nguyen, G Damiani, LAV Orenstein… - Journal of the …, 2021 - Wiley Online Library
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that severely impairs
patients' quality of life. It is characterized by recurrent painful nodules, abscesses and …

Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE): week 16 and week 52 results of two identical, multicentre, randomised …

AB Kimball, GBE Jemec, A Alavi, Z Reguiai, AB Gottlieb… - The Lancet, 2023 - thelancet.com
Background Few therapeutic options are available for patients with moderate-to-severe
hidradenitis suppurativa. We aimed to assess the efficacy of secukinumab in patients with …

[HTML][HTML] Comorbidity screening in hidradenitis suppurativa: evidence-based recommendations from the US and Canadian Hidradenitis Suppurativa Foundations

A Garg, N Malviya, A Strunk, S Wright, A Alavi… - Journal of the American …, 2022 - Elsevier
Background Hidradenitis suppurativa (HS) is associated with comorbidities that contribute to
poor health, impaired life quality, and mortality risk. Objective To provide evidence-based …

The effect of subcutaneous brodalumab on clinical disease activity in hidradenitis suppurativa: an open-label cohort study

JW Frew, K Navrazhina, D Grand… - Journal of the American …, 2020 - Elsevier
Background Hidradenitis suppurativa is an autoinflammatory disorder of keratinization, with
dysregulation of T helper type 17 cytokines. Brodalumab is a monoclonal antibody that …

Insights into hidradenitis suppurativa

KR van Straalen, EP Prens, JE Gudjonsson - Journal of Allergy and Clinical …, 2022 - Elsevier
Hidradenitis suppurativa (HS) is a chronic, debilitating, inflammatory skin disorder with a
prevalence of around 1% and a profound impact on patients' quality of life. Characteristic …

The burden of hidradenitis suppurativa signs and symptoms in quality of life: systematic review and meta-analysis

T Montero-Vilchez, P Diaz-Calvillo… - International journal of …, 2021 - mdpi.com
Hidradenitis suppurativa (HS) is a chronic, recurrent and debilitating inflammatory skin
disease of the hair follicle that usually presents as painful, deep-seated inflamed lesions in …

Biologics for hidradenitis suppurativa: evolution of the treatment paradigm

CA Maronese, C Moltrasio, G Genovese… - Expert Review of …, 2024 - Taylor & Francis
Introduction Hidradenitis suppurativa (HS) is an autoinflammatory skin disease with a high
unmet need for effective medical management. Clinically, it is characterized by inflammatory …

Pain management in hidradenitis suppurativa and a proposed treatment algorithm

KT Savage, V Singh, ZS Patel, CA Yannuzzi… - Journal of the American …, 2021 - Elsevier
Pain contributes substantially to reduced quality of life in individuals living with hidradenitis
suppurativa (HS). Although improved understanding of HS pathogenesis and treatment has …

The microbiome in hidradenitis suppurativa: a review

KJL Wark, GD Cains - Dermatology and Therapy, 2021 - Springer
Introduction Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin disease. It is
characterised by the development of abscesses and nodules in intertriginous anatomical …