Emergence of polyphagous herbivorous insects entails significant adaptation to recognize,
detoxify and digest a variety of host-plants. Despite of its biological and practical importance …

Understanding how chromatin is spatially and dynamically organized in the nucleus of
eukaryotic cells and how this affects genome functions is one of the main challenges of cell …

Orthology is a powerful refinement of homology that allows us to describe more precisely the
evolution of genomes and understand the function of the genes they contain. However …

The human sex chromosomes have stopped recombining gradually, which has left five
evolutionary strata on the X chromosome. Y inversions are thought to have suppressed X–Y …

Transposable elements (TEs) are both important drivers of genome evolution and genetic
parasites with potentially dramatic consequences for host fitness. The recent explosion of …

Abstract Background The Intergenic Breakage Model, which is the current model of
structural genome evolution, considers that evolutionary rearrangement breakages happen …

Abstract Background Polydnaviruses (PDVs) are mutualistic endogenous viruses inoculated
by some lineages of parasitoid wasps into their hosts, where they facilitate successful wasp …

For years, progress in elucidating the mechanisms underlying replication initiation and its
coupling to transcriptional activities and to local chromatin structure has been hampered by …

Background Folding and intermingling of chromosomes has the potential of bringing close to
each other loci that are very distant genomically or even on different chromosomes. On the …

Genomes undergo large structural changes that alter their organization. The chromosomal
regions affected by these rearrangements are called breakpoints, while those which have …