Role of T cells in the pathogenesis of rheumatoid arthritis: focus on immunometabolism dysfunctions
Evidence demonstrated that metabolic-associated T cell abnormalities could be detected in
the early stage of RA development. In this context, molecular evaluations have revealed …
the early stage of RA development. In this context, molecular evaluations have revealed …
From defense to offense: Modulating toll-like receptors to combat arbovirus infections
Arboviruses are a significant threat to global public health, with outbreaks occurring
worldwide. Toll-like receptors (TLRs) play a crucial role in the innate immune response …
worldwide. Toll-like receptors (TLRs) play a crucial role in the innate immune response …
Targeting TLR Signaling Cascades in Systemic Lupus Erythematosus and Rheumatoid Arthritis: An Update
Evidence from animal models and human genetics implicates Toll-like Receptors (TLRs) in
the pathogenesis of Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA) …
the pathogenesis of Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA) …
Resatorvid (TAK-242) Ameliorates Ulcerative Colitis by Modulating Macrophage Polarization and T Helper Cell Balance via TLR4/JAK2/STAT3 Signaling Pathway
Abstract Resatorvid (TAK-242), a specific inhibitor of Toll-like receptor-4 (TLR4), has
attracted attention for its anti-inflammatory properties. Despite this, few studies have …
attracted attention for its anti-inflammatory properties. Despite this, few studies have …
[HTML][HTML] TAK-242 (Resatorvid) inhibits proinflammatory cytokine production through the inhibition of NF-κB signaling pathway in fibroblast-like synoviocytes in …
Abstract Background Fibroblast-like synoviocytes (FLSs) are involved in osteoarthritis (OA)
pathogenesis through pro-inflammatory cytokine production. TAK-242, a TLR4 blocker, has …
pathogenesis through pro-inflammatory cytokine production. TAK-242, a TLR4 blocker, has …
[PDF][PDF] TAK-242 (Resatorvid) inhibits proinflammatory cytokine production through the inhibition of NF-κB signaling pathway in fibroblast-like synoviocytes in …
M Shekarabi, MN Tahmasebi, AS Vaziri… - 2024 - advancesinrheumatology …
Abstract Background Fibroblast-like synoviocytes (FLSs) are involved in osteoarthritis (OA)
pathogenesis through proinflammatory cytokine production. TAK-242, a TLR4 blocker, has …
pathogenesis through proinflammatory cytokine production. TAK-242, a TLR4 blocker, has …