The future of zoonotic risk prediction

CJ Carlson, MJ Farrell, Z Grange… - … of the Royal …, 2021 - royalsocietypublishing.org
In the light of the urgency raised by the COVID-19 pandemic, global investment in wildlife
virology is likely to increase, and new surveillance programmes will identify hundreds of …

Origins of HIV and the AIDS pandemic

PM Sharp, BH Hahn - Cold Spring …, 2011 - perspectivesinmedicine.cshlp.org
Acquired immunodeficiency syndrome (AIDS) of humans is caused by two lentiviruses,
human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2). Here, we describe the …

[图书][B] Bayesian evolutionary analysis with BEAST

AJ Drummond, RR Bouckaert - 2015 - books.google.com
What are the models used in phylogenetic analysis and what exactly is involved in Bayesian
evolutionary analysis using Markov chain Monte Carlo (MCMC) methods? How can you …

[HTML][HTML] Natural selection and infectious disease in human populations

EK Karlsson, DP Kwiatkowski, PC Sabeti - Nature Reviews Genetics, 2014 - nature.com
The ancient biological'arms race'between microbial pathogens and humans has shaped
genetic variation in modern populations, and this has important implications for the growing …

[HTML][HTML] Comparative analysis estimates the relative frequencies of co-divergence and cross-species transmission within viral families

JL Geoghegan, S Duchêne, EC Holmes - PLoS pathogens, 2017 - journals.plos.org
The cross-species transmission of viruses from one host species to another is responsible
for the majority of emerging infections. However, it is unclear whether some virus families …

A case for the ancient origin of coronaviruses

JO Wertheim, DKW Chu, JSM Peiris… - Journal of …, 2013 - Am Soc Microbiol
Coronaviruses are found in a diverse array of bat and bird species, which are believed to act
as natural hosts. Molecular clock dating analyses of coronaviruses suggest that the most …

Origin of the HIV-1 group O epidemic in western lowland gorillas

M D'arc, A Ayouba, A Esteban… - Proceedings of the …, 2015 - National Acad Sciences
HIV-1, the cause of AIDS, is composed of four phylogenetic lineages, groups M, N, O, and P,
each of which resulted from an independent cross-species transmission event of simian …

[HTML][HTML] Prisoners of war—host adaptation and its constraints on virus evolution

P Simmonds, P Aiewsakun, A Katzourakis - Nature Reviews …, 2019 - nature.com
Recent discoveries of contemporary genotypes of hepatitis B virus and parvovirus B19 in
ancient human remains demonstrate that little genetic change has occurred in these viruses …

Natural SIV hosts: showing AIDS the door

A Chahroudi, SE Bosinger, TH Vanderford, M Paiardini… - Science, 2012 - science.org
Many species of African nonhuman primates are naturally infected with simian
immunodeficiency viruses (SIVs) in the wild and in captivity. In contrast to HIV-infected …

[HTML][HTML] Population genomics of intrapatient HIV-1 evolution

F Zanini, J Brodin, L Thebo, C Lanz, G Bratt, J Albert… - Elife, 2015 - elifesciences.org
Many microbial populations rapidly adapt to changing environments with multiple variants
competing for survival. To quantify such complex evolutionary dynamics in vivo, time …