An update of human mesenchymal stem cell biology and their clinical uses
In the past decade, an increasing urge to develop new and novel methods for the treatment
of degenerative diseases where there is currently no effective therapy has lead to the …
of degenerative diseases where there is currently no effective therapy has lead to the …
Curcumin induces osteoblast differentiation through mild-endoplasmic reticulum stress-mediated such as BMP2 on osteoblast cells
HE Son, EJ Kim, WG Jang - Life sciences, 2018 - Elsevier
Aims Curcumin (diferuloylmethane or [1E, 6E]-1, 7-bis [4-hydroxy-3-methoxyphenyl]-1,
6heptadiene-3, 5-dione) is a phenolic natural product derived from the rhizomes of the …
6heptadiene-3, 5-dione) is a phenolic natural product derived from the rhizomes of the …
Increased microRNA-93-5p inhibits osteogenic differentiation by targeting bone morphogenetic protein-2
Y Zhang, QS Wei, WB Ding, LL Zhang, HC Wang… - PLoS …, 2017 - journals.plos.org
Background and purpose Trauma-induced osteonecrosis of the femoral head (TIONFH) is a
major complication of femoral neck fractures. Degeneration and necrosis of subchondral …
major complication of femoral neck fractures. Degeneration and necrosis of subchondral …
Emerging role of SMILE in liver metabolism
N Sadasivam, K Radhakrishnan, HS Choi… - International Journal of …, 2023 - mdpi.com
Small heterodimer partner-interacting leucine zipper (SMILE) is a member of the CREB/ATF
family of basic leucine zipper (bZIP) transcription factors. SMILE has two isoforms, a small …
family of basic leucine zipper (bZIP) transcription factors. SMILE has two isoforms, a small …
Strontium attenuates rhBMP-2-induced osteogenic differentiation via formation of Sr-rhBMP-2 complex and suppression of Smad-dependent signaling pathway
Abstract Strontium (Sr 2+) has pronounced effects on stimulating bone formation and
inhibiting bone resorption in bone regeneration. In this current study, the effect and the …
inhibiting bone resorption in bone regeneration. In this current study, the effect and the …
[HTML][HTML] Fat mass and obesity-associated (FTO) stimulates osteogenic differentiation of C3H10T1/2 cells by inducing mild endoplasmic reticulum stress via a positive …
HE Son, HY Min, EJ Kim, WG Jang - Molecules and cells, 2020 - Elsevier
Fat mass and obesity-associated (FTO) gene helps to regulate energy homeostasis in
mammals by controlling energy expenditure. In addition, FTO functions in the regulation of …
mammals by controlling energy expenditure. In addition, FTO functions in the regulation of …
[HTML][HTML] Cerium promotes bone marrow stromal cells migration and osteogenic differentiation via Smad1/5/8 signaling pathway
Y Hu, Y Du, H Jiang, GS Jiang - International journal of clinical and …, 2014 - ncbi.nlm.nih.gov
Cerium (Ce), one of the lanthanides (Ln), displays a variety of biochemical and physiological
effects. However, the potential effect and mechanism of Ce on bone metabolism are not well …
effects. However, the potential effect and mechanism of Ce on bone metabolism are not well …
The effects of cerium valence states at cerium oxide coatings on the responses of bone mesenchymal stem cells and macrophages
M You, K Li, Y Xie, L Huang, X Zheng - Biological trace element research, 2017 - Springer
Ideal orthopedic coatings should trigger good osteogenic response and limited inflammatory
response. The cerium valence states in ceria are associated with their anti-oxidative activity …
response. The cerium valence states in ceria are associated with their anti-oxidative activity …
The effect of atorvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (HMG-CoA), on the prevention of osteoporosis in ovariectomized rabbits
H Zhou, Y Xie, Z Baloch, Q Shi, Q Huo, T Ma - Journal of bone and mineral …, 2017 - Springer
Osteoporosis is a most frequent systemic skeletal disease characterized as low bone
mineral density and microarchitectural deterioration of bone tissue, resulting in increased …
mineral density and microarchitectural deterioration of bone tissue, resulting in increased …
Calcium ion-induced formation of β-sheet/-turn structure leading to alteration of osteogenic activity of bone morphogenetic protein-2
W Zhang, H He, Y Tian, Q Gan, J Zhang, Y Yuan… - Scientific reports, 2015 - nature.com
Preserving bioactivity of bone morphogenetic protein 2 (BMP-2) still remains a challenge in
protein-based therapy. It is not known how Ca2+ released from extracellular matrix or …
protein-based therapy. It is not known how Ca2+ released from extracellular matrix or …