Purpose: Retrospective analysis of irAEs in melanoma patients treated with nivolumab.
Experimental Design: Data were pooled from 148 patients (33 resected, 115 unresectable) …

Aberrations in cell signal transduction pathways, including EGFR, MAPK (RAS-RAF-MEK-
ERK), and PI3K-Akt-mTOR, play an essential role in tumorigenesis and disease …

Problem Identification: Patients with cancer experience multiple symptoms, but current
practice is driven by guidelines that address single symptoms. Identifying symptom …

An increase in the incidence of melanoma has been observed in recent decades, which
poses a significant challenge due to its poor prognosis in the advanced and metastatic …

Therapies for advanced non‐small cell lung cancer (NSCLC) continue to become more
sophisticated. Chemotherapeutics are giving way to newer approaches such as immune …

Background: Agents targeting the MAPK pathway, including inhibitors of BRAF and MEK,
have dramatically transformed the treatment landscape for patients with BRAF-mutant …

Breast adenocarcinoma (BAC) in glandular tissue cells have excessive metastasis and
invasion capability. The major challenges for the chemotherapy used for the management of …

Problem Identification: Patients with cancer experience multiple symptoms, but current
practice is driven by guidelines that address single symptoms. Identifying symptom …

Zespół erytrodyzestezji dłoniowo-podeszwowej (zespół ręka–stopa) to częste działanie
niepożądane niektórych klasycznych chemioterapeutyków, a także leków celowanych …

Zespół erytrodyzestezji dłoniowo-podeszwowej, zwany inaczej zespołem ręka–stopa, może
rozwinąć się jako działanie niepożądane terapii przeciwnowotworowych z zastosowaniem …