The repression of the HMGB1-TLR4-NF-κB signaling pathway by safflower yellow may improve spinal cord injury

L Wang, BOA Botchway, X Liu - Frontiers in Neuroscience, 2021 - frontiersin.org
Spinal cord injury (SCI) often results in abnormal sensory and motor functions. Current
interventions for SCI in the clinical setting are not effective partly due to the complexity …

The inhibition of inflammatory signaling pathway by secretory leukocyte protease inhibitor can improve spinal cord injury

R Tang, BOA Botchway, Y Meng, Y Zhang… - Cellular and molecular …, 2020 - Springer
Spinal cord injury leads to loss of sensory motor functions below the damaged area, and can
significantly affects physical and mental health. An effective spinal cord injury treatment is …

Therapeutic effect of metformin on inflammation and apoptosis after spinal cord injury in rats through the Wnt/β-catenin signaling pathway

T Zhang, F Wang, K Li, C Lv, K Gao, C Lv - Neuroscience Letters, 2020 - Elsevier
Objective To verify the effect of metformin on spinal cord injury (SCI) through Wnt/β-catenin
signaling pathway. Background SCI is a serious traumatic disease of the central nervous …

Neuroprotective effects of dexpanthenol on rabbit spinal cord ischemia/reperfusion injury model

A Gülmez, PK Bektaşoğlu, Ç Tönge, A Yaprak… - World Neurosurgery, 2022 - Elsevier
Objective Dexpanthenol (DXP) reportedly protects tissues against oxidative damage in
various inflammation models. This study aimed to evaluate its effects on oxidative stress …

Protective effect of alpha‐lipoic acid against apical periodontitis‐induced cardiac injury in rats

AÖ Sehirli, U Aksoy, F Kermeoglu… - European journal of …, 2019 - Wiley Online Library
This study was designed to assess the possible protective effect of alpha‐lipoic acid (ALA)
on apical periodontitis (AP)‐induced cardiac injury. Wistar albino rats were randomized into …

[HTML][HTML] Cinnamaldehyde has ameliorative effects on rabbit spinal cord ischemia and reperfusion injury

PK Bektaşoğlu, AT Arıkök, Bİ Ergüder, MF Sargon… - World Neurosurgery …, 2024 - Elsevier
During thoracoabdominal aortic surgery, blood supply to the spinal cord may be interrupted,
resulting in ischemia, and when blood flow is restored, reperfusion occurs. This process will …

Phosphoglycerate mutase 1 prevents neuronal death from ischemic damage by reducing neuroinflammation in the rabbit spinal cord

HY Jung, HJ Kwon, W Kim, KR Hahn, SM Moon… - International Journal of …, 2020 - mdpi.com
Phosphoglycerate mutase 1 (PGAM1) is a glycolytic enzyme that increases glycolytic flux in
the brain. In the present study, we examined the effects of PGAM1 in conditions of oxidative …

Effects of ADSC-Derived Exosome LRRC75A-AS1 on Anti-inflammatory Function After SCI

X Xing, P Xu, X Xing, Z Xu, Z Huang, Z Li, X Li… - Applied Biochemistry …, 2024 - Springer
Spinal cord injury (SCI) is a highly debilitating disorder of the central nervous system that
can severely impact an affected patient's quality of life. This study aimed to examine how …

Effectiveness of Pharmacotherapy in Reducing the Inflammation Process of Spinal Cord Injuries: A Systematic Review of Animal Studies

EA Subagio, P Wicaksono, A Asadullah… - The Scientific World …, 2024 - Wiley Online Library
Background: Currently, there is no gold standard technique in SCI therapy. Although there
have been many systematic reviews on the pharmacological treatment of inflammation in …

[PDF][PDF] Sesamin ameliorates mucosal tissue injury of mesenteric ischemia and reperfusion in an experimental rat model

M Sayhan, S Oguz, Ö Salt, N Can, T Ozgurtas… - Archives of Medical …, 2019 - termedia.pl
Results Plasma and tissue total antioxidant status (TAS) levels were significantly higher in
I/R+ S group compared to the rest (p< 0.005). The plasma TAS levels in I/R group was …