Long non-coding RNAs as epigenetic regulators in cancer

A Vafadar, Z Shabaninejad… - Current …, 2019 - ingentaconnect.com
Long noncoding RNAs (lncRNAs) constitute large portions of the mammalian transcriptome
which appeared as a fundamental player, regulating various cellular mechanisms. LncRNAs …

Potential diagnostic, prognostic and therapeutic targets of microRNAs in human gastric cancer

MM Tsai, CS Wang, CY Tsai, HW Huang… - International journal of …, 2016 - mdpi.com
Human gastric cancer (GC) is characterized by a high incidence and mortality rate, largely
because it is normally not identified until a relatively advanced stage owing to a lack of early …

Long non-coding RNA UCA1 promotes cisplatin/gemcitabine resistance through CREB modulating miR-196a-5p in bladder cancer cells

J Pan, XU Li, W Wu, M Xue, H Hou, W Zhai, W Chen - Cancer letters, 2016 - Elsevier
Chemoresistance constitutes the major failing of clinical therapy for bladder cancer.
However, the molecular mechanisms involved in the chemoresistance of bladder cancer are …

MicroRNA-196a2 biomarker and targetome network analysis in solid tumors

EA Toraih, MS Fawzy, EA Mohammed… - Molecular diagnosis & …, 2016 - Springer
Introduction MicroRNAs (miRNAs) have been linked to cancer development and
progression. The molecular mechanisms underlying the genetic associations of the miRNA …

A feature-based analysis identifies COL1A2 as a regulator in pancreatic cancer

J Wu, J Liu, XQ Wei, Q Yu, XH Niu… - Journal of enzyme …, 2019 - Taylor & Francis
This study aimed to identify genetic biomarkers in pancreatic cancer (PC) and explore its
function in PC via a feature-base analysis of bioinformatics. OMIM and DisGeNET databases …

Evaluation of miRNA-196a2 and apoptosis-related target genes: ANXA1, DFFA and PDCD4 expression in gastrointestinal cancer patients: A pilot study

MS Fawzy, EA Toraih, A Ibrahiem, H Abdeldayem… - PloS one, 2017 - journals.plos.org
Previous reports have suggested the significant association of miRNAs aberrant expression
with tumor initiation, progression and metastasis in cancer, including gastrointestinal (GI) …

Serum exosomal microRNA-370-3p and microRNA-196a-5p are potential biomarkers for the diagnosis and prognosis of hepatocellular carcinoma

Y Wei, Q Zhang, L An, G Fang, D Hong… - Folia Histochemica …, 2022 - journals.viamedica.pl
Introduction. Evidence has shown that some microRNAs (miRNAs) play a role in
tumorigenesis of hepatocellular carcinoma (HCC). Herein, we aimed to evaluate the …

[HTML][HTML] Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells

I Guerriero, D D'Angelo, P Pallante, M Santos… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Hyperactivation of the PI3K/AKT pathway is observed in most human cancer including lung
carcinomas. Here we have investigated the role of miRNAs as downstream targets of …

Dynamics of MiRNA Transcriptome in Turbot (Scophthalmus maximus L.) Intestine Following Vibrio anguillarum Infection

C Gao, X Cai, Q Fu, N Yang, L Song, B Su, F Tan… - Marine …, 2019 - Springer
MicroRNAs (miRNAs) are a group of small non-coding RNAs, which could bind to the 3′-
untranslated regions of their target mRNAs to regulate gene expression in various biological …

[HTML][HTML] Comparison of prognostic microRNA biomarkers in blood and tissues for gastric cancer

W Yan, L Qian, J Chen, W Chen, B Shen - Journal of Cancer, 2016 - ncbi.nlm.nih.gov
Gastric cancer (GC) still keeps up high mortality worldwide with poor prognosis. Efficient and
non-invasive prognostic biomarkers are urgently needed. MicroRNAs are non-coding RNAs …