Distinct mechanisms of CB1 and GABAB receptor presynaptic modulation of striatal indirect pathway projections to mouse globus pallidus
G Sitzia, KP Abrahao, D Liput… - The Journal of …, 2023 - Wiley Online Library
Presynaptic modulation is a fundamental process regulating synaptic transmission. Striatal
indirect pathway projections originate from A2A‐expressing spiny projection neurons …
indirect pathway projections originate from A2A‐expressing spiny projection neurons …
Anxa1+ dopamine neuron vulnerability defines prodromal Parkinson's disease bradykinesia and procedural motor learning impairment
Progressive degeneration of dopamine neurons (DANs) defines Parkinson's disease (PD).
However, the identity and function of the most vulnerable DAN populations in prodromal PD …
However, the identity and function of the most vulnerable DAN populations in prodromal PD …
Model of a striatal circuit exploring biological mechanisms underlying decision-making during normal and disordered states
DW Beck, CN Heaton, LD Davila, LI Rakocevic… - bioRxiv, 2024 - biorxiv.org
Decision-making requires continuous adaptation to internal and external contexts. Changes
in decision-making are reliable transdiagnostic symptoms of neuropsychiatric disorders. We …
in decision-making are reliable transdiagnostic symptoms of neuropsychiatric disorders. We …
[图书][B] The circuit and synaptic organization of the basal ganglia output: mechanistic insights on movement disorders and action control
G Sitzia - 2022 - search.proquest.com
Understanding the neural circuitry underlying movement is a neuroscientific challenge that
promises to help refining currently available treatments for movement disorders. Key …
promises to help refining currently available treatments for movement disorders. Key …
[图书][B] A Critic in Action? A Functional Examination of the Striato-pallido-habenular Circuit
M Weglage - 2022 - search.proquest.com
The basal ganglia (BG) and the midbrain dopamine (DA) system are consideredkey loci of
reinforcement learning (RL), or learning by" trial and error", inthe brain. The BG are …
reinforcement learning (RL), or learning by" trial and error", inthe brain. The BG are …