Role of chemotherapy and targeted therapy in early-stage non-small cell lung cancer

M Nagasaka, SM Gadgeel - Expert review of anticancer therapy, 2018 - Taylor & Francis
Introduction: Adjuvant platinum based chemotherapy is accepted as standard of care in
stage II and III non-small cell lung cancer (NSCLC) patients and is often considered in …

[HTML][HTML] The IASLC lung cancer staging project: proposals for the revisions of the T descriptors in the forthcoming eighth edition of the TNM classification for lung …

R Rami-Porta, V Bolejack, J Crowley, D Ball… - Journal of Thoracic …, 2015 - Elsevier
Introduction: An international database was collected to inform the 8 th edition of the
anatomic classification of lung cancer. The present analyses concern its primary tumor (T) …

The impact of visceral pleural invasion in node-negative non-small cell lung cancer: a systematic review and meta-analysis

L Jiang, W Liang, J Shen, X Chen, X Shi, J He, C Yang… - Chest, 2015 - Elsevier
BACKGROUND Visceral pleural invasion (VPI) is considered an aggressive and invasive
factor in non-small cell lung cancer (NSCLC). Recent studies found that depending on tumor …

Visceral pleural invasion remains a size-independent prognostic factor in stage I non-small cell lung cancer

H Huang, T Wang, B Hu, C Pan - The Annals of thoracic surgery, 2015 - Elsevier
Background The prognostic effect of visceral pleural invasion remains controversial when a
tumor is less than 3 cm in stage I non-small cell lung cancer patients. We conducted this …

Predictive and prognostic biomarkers in non-small cell lung cancer

MK Thakur, SM Gadgeel - Seminars in respiratory and critical …, 2016 - thieme-connect.com
Therapy of non-small cell lung cancer (NSCLC) patients has evolved over the past few years
with the incorporation of targeted therapy and immune therapy. These changes have …

Clinicopathologic and prognostic significance of c-MYC copy number gain in lung adenocarcinomas

AN Seo, JM Yang, H Kim, S Jheon, K Kim… - British journal of …, 2014 - nature.com
Background: c-MYC copy number gain (c-MYC gain) has been associated with aggressive
behaviour in several cancers. However, the role of c-MYC gain has not yet been determined …

Association between high-resolution computed tomography findings and the IASLC/ATS/ERS classification of small lung adenocarcinomas in Japanese patients

Y Kudo, J Matsubayashi, H Saji, S Akata, Y Shimada… - Lung Cancer, 2015 - Elsevier
Objectives The detection rate of small pulmonary nodules has recently increased and new
techniques have been developed to improve diagnostic yield. The IASLC/ATS/ERS …

Prognostic significance of ground-glass opacity components in 5-year survivors with resected lung adenocarcinoma

S Shigefuku, Y Shimada, M Hagiwara… - Annals of Surgical …, 2021 - Springer
Background Reports on the prognosis for 5-year survivors with lung adenocarcinoma after
resection are sparse. This study aimed to identify factors associated with overall survival …

Overall Survival Among Patients With De Novo Stage IV Metastatic and Distant Metastatic Recurrent Non–Small Cell Lung Cancer

CC Su, JT Wu, E Choi, NJ Myall, JW Neal… - JAMA Network …, 2023 - jamanetwork.com
Importance Despite recent breakthroughs in therapy, advanced lung cancer still poses a
therapeutic challenge. The survival profile of patients with metastatic lung cancer remains …

Implications of False Negative and False Positive Diagnosis in Lymph Node Staging of NSCLC by Means of 18F-FDG PET/CT

S Li, Q Zheng, Y Ma, Y Wang, Y Feng, B Zhao, Y Yang - PloS one, 2013 - journals.plos.org
Background Integrated 18F-fluorodeoxyglucose positron emission tomography/computed
tomography (18F-FDG PET/CT) is widely performed in hilar and mediastinal lymph node …