Functional electrospun fibers for local therapy of cancer

J Zhao, W Cui - Advanced Fiber Materials, 2020 - Springer
Despite great efforts and advancement in the treatment of cancer, tumor recurrence and
metastasis remain significant challenges and demand novel therapy strategies. Recently …

Drug-loaded biomaterials for orthopedic applications: A review

D Aggarwal, V Kumar, S Sharma - Journal of Controlled Release, 2022 - Elsevier
Drug-eluting implants are one of the leading implant technologies to facilitate the healing
capacity of bones by eliminating implant-associated infections. Treatment of the infections …

NIR-II-triggered composite nanofibers to simultaneously achieve intracranial hemostasis, killing superbug and residual cancer cells in brain tumor resection surgery

J Yang, L Xu, Y Ding, C Liu, B Wang, Y Yu, C Hui… - Advanced Fiber …, 2023 - Springer
Malignant glioblastoma (GBM) is prone to relapse due to the inevitable tumor cells residue
by surgery. During the tumor resection surgery in brain, addressing bleeding and superbug …

Advances in drug delivery for post-surgical cancer treatment

LL Bu, J Yan, Z Wang, H Ruan, Q Chen, V Gunadhi… - Biomaterials, 2019 - Elsevier
Surgery remains a primary modality of treatment for the majority of solid tumor malignancies.
While advancements in surgical technique and instrumentation have improved the quality of …

Rationally designed drug delivery systems for the local treatment of resected glioblastoma

C Bastiancich, A Malfanti, V Préat, R Rahman - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is a particularly aggressive brain cancer associated with high
recurrence and poor prognosis. The standard of care, surgical resection followed by …

Polysaccharide based scaffolds for soft tissue engineering applications

S Tiwari, R Patil, P Bahadur - Polymers, 2018 - mdpi.com
Soft tissue reconstructs require materials that form three-dimensional (3-D) structures
supportive to cell proliferation and regenerative processes. Polysaccharides, due to their …

Evolution of drug-eluting biomedical implants for sustained drug delivery

JC Quarterman, SM Geary, AK Salem - European Journal of Pharmaceutics …, 2021 - Elsevier
In the field of drug delivery, the most commonly used treatments have traditionally been
systemically delivered using oral or intravenous administration. The problems associated …

Drug delivery across the blood-brain barrier for the treatment of pediatric brain tumors–An update

EA Power, JS Rechberger, S Gupta… - Advanced drug delivery …, 2022 - Elsevier
Even though the last decade has seen a surge in the identification of molecular targets and
targeted therapies in pediatric brain tumors, the blood brain barrier (BBB) remains a …

A predictive mechanistic model of drug release from surface eroding polymeric nanoparticles

RT Stiepel, ES Pena, SA Ehrenzeller… - Journal of controlled …, 2022 - Elsevier
Effective drug delivery requires ample dosing at the target tissue while minimizing negative
side effects. Drug delivery vehicles such as polymeric nanoparticles (NPs) are often …

Electrospray for generation of drug delivery and vaccine particles applied in vitro and in vivo

RT Steipel, MD Gallovic, CJ Batty, EM Bachelder… - Materials Science and …, 2019 - Elsevier
Also known as electrospray, electrohydrodynamic atomization has been used extensively in
the last 15 years to develop polymer-based particles for drug delivery in cell and animal …