In multicellular organisms, the total number of cells is a balance between the cell-generating
effects of mitosis and cell death that is induced through apoptosis. A disruption of this …

Chloroquine (CQ), N′-(7-chloroquinolin-4-yl)-N, N-diethyl-pentane-1, 4-diamine, is widely
used as an effective and safe anti-malarial and anti-rheumatoid agent. CQ was discovered …

Cell death is a fundamental ingredient of life. Thus, not surprisingly more than one form of
cell death exists. Several excellent reviews on various forms of cell death have already been …

Head and neck cancer (HNC) is an ascending and agressive disease. The search for new
molecular markers is emerging to solve difficulties in diagnosis, risk management, prognosis …

Apoptosis, the cell's intrinsic death program, is a key regulator of tissue homeostasis. An
imbalance between cell death and proliferation may result in tumor formation. Also, killing of …

Abstract microRNAs (miRNAs) are highly conserved, non‐protein‐coding RNAs that function
to regulate gene expression. In mammals this regulation is primarily carried out by …

Disruption of apoptosis may allow metastatic cell survival and confer resistance to
chemotherapeutic drugs. We have analysed the molecular pathways that activate these …

MicroRNAs (miRNAs) are small, non-coding, endogenous RNAs that regulate gene
expression at the post-transcriptional level. MiRNAs play important roles in regulating a …

It is well known that dysfunction of the apoptotic pathway confers apoptosis resistance and
results in a low sensitivity of human cancer cells to therapeutic agents. A novel strategy to …

Studies of apoptosis in breast cancer | The BMJ Skip to main content Intended for healthcare
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