T cell responses to SARS-CoV-2
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines
Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …
previous infections. Immunological memory can develop from multiple branches of the …
Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant
The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Omicron (B. 1.1. 529) variant of concern (VOC) has destabilized global efforts to control the …
Omicron (B. 1.1. 529) variant of concern (VOC) has destabilized global efforts to control the …
The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
Correlates of protection against SARS‐CoV‐2 infection and COVID‐19 disease
D Goldblatt, G Alter, S Crotty… - Immunological reviews, 2022 - Wiley Online Library
Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans
U Sahin, A Muik, I Vogler, E Derhovanessian, LM Kranz… - Nature, 2021 - nature.com
Abstract BNT162b2, a nucleoside-modified mRNA formulated in lipid nanoparticles that
encodes the SARS-CoV-2 spike glycoprotein (S) stabilized in its prefusion conformation, has …
encodes the SARS-CoV-2 spike glycoprotein (S) stabilized in its prefusion conformation, has …
[HTML][HTML] Impact of SARS-CoV-2 variants on the total CD4+ and CD8+ T cell reactivity in infected or vaccinated individuals
The emergence of SARS-CoV-2 variants with evidence of antibody escape highlight the
importance of addressing whether the total CD4+ and CD8+ T cell recognition is also …
importance of addressing whether the total CD4+ and CD8+ T cell recognition is also …
SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients
D Geers, MC Shamier, S Bogers, G den Hartog… - Science …, 2021 - science.org
The emergence of SARS-CoV-2 variants harboring mutations in the spike (S) protein has
raised concern about potential immune escape. Here, we studied humoral and cellular …
raised concern about potential immune escape. Here, we studied humoral and cellular …
Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study
L Monin, AG Laing, M Muñoz-Ruiz… - The Lancet …, 2021 - thelancet.com
Background The efficacy and safety profiles of vaccines against SARS-CoV-2 in patients
with cancer is unknown. We aimed to assess the safety and immunogenicity of the …
with cancer is unknown. We aimed to assess the safety and immunogenicity of the …
SARS-CoV-2, COVID-19 and the aging immune system
JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …
particular risk for severe disease and death in older adults and in adults with age-related …