Damage-associated molecular patterns are signalling molecules involved in inflammatory
responses and restoration of homeostasis. Chronic release of these molecules can also …

Deregulations of the expression of the S100A8 and S100A9 genes and/or proteins, as well
as changes in their plasma levels or their levels of secretion in the bone marrow …

Hepatocellular Carcinoma (HCC) is one of the most predominant malignancies with high
fatality rate. This deadly cancer is rising at an alarming rate because it is quite resistant to …

Inflammation primarily influences the initiation, progression, and deterioration of many
human diseases, and immune cells are the principal forces that modulate the balance of …

Abstract Each year, almost 4.1 million people are diagnosed with gastrointestinal (GI)
cancers. Due to late detection of this disease, the mortality is high, causing approximately 3 …

Some long noncoding RNAs (lncRNAs) display aberrantly high or low expression in
hepatocellular carcinoma (HCC) and have the potential to serve as diagnostic biomarkers …

Background Suppressor of cytokine signaling (SOCS) 1 and 3 methylation have been
associated with clinical features and outcomes of cancer patients. However, their roles in …

Overexpression of pyrroline-5-carboxylate reductase 1 (PYCR1) has been associated with
the development of certain cancers; however, no studies have specifically examined the role …

Background S100A8 plays a key role in many cellular processes and is highly expressed in
various solid cancers. However, the prognostic role of S100A8 has not been well defined …

DNA methylation is one of the main epigenetic modifications. It controls gene expression
through altering chromosomal structure, DNA conformation, DNA stability and the function …