Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Nanomedicines have the potential to provide advanced therapeutic strategies in combating
tumors. Polymer‐prodrug‐based nanomedicines are particularly attractive in cancer …

The clinical application of chemotherapy is impeded by the unsatisfactory efficacy and
severe side effects. Chemodynamic therapy (CDT) has emerged as an efficient strategy for …

Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …

Reactive oxygen species (ROS) can be used not only as a therapeutic agent for
chemodynamic therapy (CDT), but also as a stimulus to activate release of antitumor drugs …

The incorporation of new modalities into chemotherapy greatly enhances the anticancer
efficacy combining the merits of each treatment, showing promising potentials in clinical …

Owing to the complex and still not fully understood physiological environment, the
development of traditional nanosized drug delivery systems is very challenging for precision …

Nanomedicines overcome the pharmacokinetic limitations of traditional drug formulations
and have promising prospect in cancer treatment. However, nanomedicine delivery in vivo is …

The requirement for the favorable therapeutics against ulcerative colitis (UC) is that anti-
inflammatory drugs can be specifically internalized by macrophages and subsequently be …

Patient-derived xenograft (PDX) models are powerful tools for understanding cancer biology
and drug discovery. In this study, a polymeric nano-sized drug delivery system poly …