Use of Resonant Acoustic Mixing Technology for Ultra-Low-Dose Blending in a Single-Step Mixing Process

KA Frey, H Baker, DK Purcell, AL Lewis… - Pharmaceutical …, 2024 - Springer
Purpose To evaluate the use of resonant acoustic mixing (RAM) technology for homogenous
blending of a morphologically challenging model API in low-dose concentrations (< 0.1 …

[HTML][HTML] Solid Forms of Bio-Based Monomer Salts for Polyamide 512 and Their Effect on Polymer Properties

X Zhang, X Fang, Y Yan, Z Li, Q Wen, K Zhang, M Li… - Polymers, 2024 - mdpi.com
Polyamides' properties are greatly influenced by the polymerization process and the type of
feedstock used. The solid forms of nylon salts play a significant role in determining the final …

How do morphological changes of caffeine hydrate influence caking

P Cui, Y Liu, L Jia, L Zhou, Q Yin - Journal of Food Engineering, 2023 - Elsevier
Morphological changes in hydrates during the drying process can cause various potential
problems. The crystal properties of caffeine, such as morphology and particle size …

[HTML][HTML] Evaluation of two and three fluid nozzle spray drying to prepare co-crystals of salicylic acid and caffeine with improved physicochemical properties

T Hibbard, K Shankland, H Al-Obaidi - Journal of Drug Delivery Science …, 2023 - Elsevier
Formation of co-crystals using spray drying remains a challenging task due to the rapid
nature of the process and the possible impact of solvents on the formation of the co-crystals …

Monitoring temporal evolution of the dehydration process of the caffeine hydrate with terahertz spectroscopy

H Park, N Kim, J Yu, J Rhie, G Choi… - Journal of the Korean …, 2022 - Springer
Drugs or foods in various forms, such as hydrate and anhydrous forms, can affect the
different therapeutic effect, which is crucial to identify pseudo-polymorphic state. Caffeine …

From Microdroplets to Microcrystals: Tunable Caffeine Particles by Spray Flash Evaporation

Y Busby, E Lobry, F Schnell, G Galland… - Crystal Growth & …, 2021 - ACS Publications
In this work, tunable caffeine crystals are formulated through a promising aerosol-based
technology called spray flash evaporation (SFE). In this process, the vacuum atomization of …

Non-Invasive Structural Analysis of Packaged Pharmaceuticals Using Different Variants of Spatially Offset Low-Frequency Raman Spectroscopy

K Bērziņš, L Krog, B Boyd - Available at SSRN 5007494 - papers.ssrn.com
Three different variants of low-frequency Raman (LFR) spectroscopy (< 300 cm-1) with
spatially offset configurations were explored for the in situ analysis of packaged …