Combined oncolytic virotherapy and immunotherapy (immunovirotherapy) protocols
represent a promising treatment strategy for a range of cancers and offer many advantages …

Oncolytic viruses are genetically engineered to treat growing tumours and represent a very
promising therapeutic strategy. Using a Gompertz growth law, we discuss a model that …

V937 is an investigational novel oncolytic non-genetically modified Kuykendall strain of
Coxsackievirus A21 which is in clinical development for the treatment of advanced solid …

Oncolytic virotherapy is a promising cancer treatment using genetically modified viruses.
Unfortunately, virus particles rapidly decay inside the body, significantly hindering their …

Combining chimeric antigen receptor T (CAR-T) cells with oncolytic viruses (OVs) has
recently emerged as a promising treatment approach in preclinical studies that aim to …

In this paper, we propose a delayed mathematical model describing oncolytic virotherapy
treatment of a tumour that proliferates according to the logistic growth function, incorporating …

1. Introduction e therapy for cancer is determined on the stage of the disease. e TNM
technique is used to describe the stage of cancer depending on the growth of tumor (T) and …

We present a system of four nonlinear differential equations to model the use of virotherapy
as a treatment for cancer. This model describes interactions among infected tumor cells …

Virotherapy is a novel treatment for cancer, which may be delivered as a single agent or in
combination with other therapies. Research studies indicated that the combination of viral …

The use of oncolytic viruses as cancer treatment has received considerable attention in
recent years, however the spatial dynamics of this viral infection is still poorly understood …