Quantitative and qualitative differences in the activation of a fibroblast growth factor receptor by different FGF ligands

MA Krzyscik, K Karl, P Dudeja, P Krejci… - Cytokine & Growth Factor …, 2024 - Elsevier
The FGF system is the most complex of all receptor tyrosine kinase signaling networks with
18 FGF ligands and four FGFRs that deliver morphogenic signals to pattern most embryonic …

Spatial transcriptomics reveals molecular cues underlying the site specificity of the adult mouse oral mucosa and its stem cell niches

AC Seubert, M Krafft, S Bopp, M Helal, P Bhandare… - Stem Cell Reports, 2024 - cell.com
The oral cavity is a multifunctional organ composed of structurally heterogeneous mucosal
tissues that remain poorly characterized. Oral mucosal tissues are highly stratified and …

AI-powered simulation-based inference of a genuinely spatial-stochastic gene regulation model of early mouse embryogenesis

MA Ramirez Sierra, TR Sokolowski - PLOS Computational Biology, 2024 - journals.plos.org
Understanding how multicellular organisms reliably orchestrate cell-fate decisions is a
central challenge in developmental biology, particularly in early mammalian development …

Cordycepin Activates Autophagy to Suppress FGF9-induced TM3 Mouse Leydig Progenitor Cell Proliferation

SZ Wu, YY Lan, CY Chen, LC Chen… - Cancer Genomics & …, 2024 - cgp.iiarjournals.org
Background/Aim: Fibroblast growth factor 9 (FGF9) is a member of the human FGF family
known for its pivotal roles in various biological processes, such as cell proliferation, tissue …