[HTML][HTML] Advances and trends in omics technology development
X Dai, L Shen - Frontiers in Medicine, 2022 - frontiersin.org
The human history has witnessed the rapid development of technologies such as high-
throughput sequencing and mass spectrometry that led to the concept of 'omics' and …
throughput sequencing and mass spectrometry that led to the concept of 'omics' and …
Potential resistance of SARS-CoV-2 main protease (Mpro) against protease inhibitors: lessons learned from HIV-1 protease
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome 2
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …
Search and sequence analysis tools services from EMBL-EBI in 2022
F Madeira, M Pearce, ARN Tivey… - Nucleic acids …, 2022 - academic.oup.com
The EMBL-EBI search and sequence analysis tools frameworks provide integrated access to
EMBL-EBI's data resources and core bioinformatics analytical tools. EBI Search …
EMBL-EBI's data resources and core bioinformatics analytical tools. EBI Search …
Structure and mutations of SARS-CoV-2 spike protein: a focused overview
The spike protein (S-protein) of SARS-CoV-2, the protein that enables the virus to infect
human cells, is the basis for many vaccines and a hotspot of concerning virus evolution …
human cells, is the basis for many vaccines and a hotspot of concerning virus evolution …
COVID19db: a comprehensive database platform to discover potential drugs and targets of COVID-19 at whole transcriptomic scale
W Zhang, Y Zhang, Z Min, J Mo, Z Ju… - Nucleic acids …, 2022 - academic.oup.com
Many open access transcriptomic data of coronavirus disease 2019 (COVID-19) were
generated, they have great heterogeneity and are difficult to analyze. To utilize these …
generated, they have great heterogeneity and are difficult to analyze. To utilize these …
SARS‐CoV‐2 structural coverage map reveals viral protein assembly, mimicry, and hijacking mechanisms
We modeled 3D structures of all SARS‐CoV‐2 proteins, generating 2,060 models that span
69% of the viral proteome and provide details not available elsewhere. We found that˜ 6% of …
69% of the viral proteome and provide details not available elsewhere. We found that˜ 6% of …
[HTML][HTML] Applying the digital data and the bioinformatics tools in SARS-CoV-2 research
M Tan, J Xia, H Luo, G Meng, Z Zhu - Computational and Structural …, 2023 - Elsevier
Bioinformatics has been playing a crucial role in the scientific progress to fight against the
pandemic of the coronavirus disease 2019 (COVID-19) caused by the severe acute …
pandemic of the coronavirus disease 2019 (COVID-19) caused by the severe acute …
[HTML][HTML] Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses
Viruses often encode proteins that mimic host proteins in order to facilitate infection. Little
work has been done to understand the potential mimicry of the SARS-CoV-2, SARS-CoV …
work has been done to understand the potential mimicry of the SARS-CoV-2, SARS-CoV …
Structures of the SARS-CoV-2 spike glycoprotein and applications for novel drug development
XH Liu, T Cheng, BY Liu, J Chi, T Shu… - Frontiers in …, 2022 - frontiersin.org
COVID-19 caused by SARS-CoV-2 has raised a health crisis worldwide. The high morbidity
and mortality associated with COVID-19 and the lack of effective drugs or vaccines for SARS …
and mortality associated with COVID-19 and the lack of effective drugs or vaccines for SARS …
Next-generation bioinformatics approaches and resources for coronavirus vaccine discovery and development—A perspective review
COVID-19 is a contagious disease caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). To fight this pandemic, which has caused a massive death toll …
coronavirus 2 (SARS-CoV-2). To fight this pandemic, which has caused a massive death toll …