Label-free macrophage phenotype classification using machine learning methods

T Hourani, A Perez-Gonzalez, K Khoshmanesh… - Scientific Reports, 2023 - nature.com
Macrophages are heterogeneous innate immune cells that are functionally shaped by their
surrounding microenvironment. Diverse macrophage populations have multifaceted …

Cryoprecipitate attenuates the endotheliopathy of trauma in mice subjected to hemorrhagic shock and trauma

M Barry, A Trivedi, BY Miyazawa… - Journal of Trauma …, 2021 - journals.lww.com
BACKGROUND Plasma has been shown to mitigate the endotheliopathy of trauma.
Protection of the endothelium may be due in part to fibrinogen and other plasma-derived …

TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis

J Li, C Liang, ZK Zhang, X Pan, S Peng, WS Lee, A Lu… - Cell Discovery, 2017 - nature.com
Pneumoconiosis, caused by inhalation of mineral dusts, is a major occupational disease
worldwide. Currently, there are no effective drugs owing to a lack of potential therapeutic …

Length-dependent toxicity of TiO2 nanofibers: mitigation via shortening

MG Bianchi, L Campagnolo, M Allegri, S Ortelli… - …, 2020 - Taylor & Francis
Length and aspect ratio represent important toxicity determinants of fibrous nanomaterials.
We have previously shown that anatase TiO2 nanofibers (TiO2 NF) cause a dose …

Chronic lung inflammation primes humoral immunity and augments antipneumococcal resistance

JD Boehme, S Stegemann-Koniszewski… - Scientific Reports, 2017 - nature.com
Airway epithelial cells (AECs) display remarkable plasticity in response to infectious stimuli
and their functional adaptations are critical for antimicrobial immunity. However, the roles of …

CD47 restricts antiviral function of alveolar macrophages during influenza virus infection

C Wenzek, P Steinbach, F Wirsdörfer, K Sutter… - Iscience, 2022 - cell.com
CD47 is an ubiquitously expressed surface molecule with significant impact on immune
responses. However, its role for antiviral immunity is not fully understood. Here, we revealed …

[HTML][HTML] Evaluation of the immunomodulatory activity of thalidomide on tumor-associated macrophages in the 4T1 murine metastatic breast cancer model

DC Reis, MA Rodrigues, SGB Pinto… - Arquivo Brasileiro de …, 2021 - SciELO Brasil
The present work evaluated the immunomodulatory effect of thalidomide (Thal) at different
doses on tumor-associated macrophages (TAMs) using a mouse model of human breast …

Cellular Mechanisms of Angiotensin II Type-2 Receptor Activation in Protecting Against Chronic Obstructive Pulmonary Disease

M Dan - 2021 - search.proquest.com
Chronic obstructive pulmonary diseases (COPD) is a major medical problem and huge
economic burden to the society. COPD affects more than 384 million people worldwide and …

[PDF][PDF] Makrophagen im Kontext des allergischen Asthma bronchiale

J Dunkel - zhb.uni-luebeck.de
1 Zusammenfassung Die Entwicklung in der Forschung rund um das allergische Asthma
bronchiale zeigt, dass den zuvor stiefmütterlich behandelten Makrophagen eine immer …