Reverse cholesterol transport: molecular mechanisms and the non-medical approach to enhance HDL cholesterol

LR Marques, TA Diniz, BM Antunes, FE Rossi… - Frontiers in …, 2018 - frontiersin.org
Dyslipidemia (high concentrations of LDL-c and low concentrations of HDL-c) is a major
cause of cardiovascular events, which are the leading cause of death in the world. On the …

Role of ABCA1 in Cardiovascular Disease

J Wang, Q Xiao, L Wang, Y Wang, D Wang… - Journal of Personalized …, 2022 - mdpi.com
Cholesterol homeostasis plays a significant role in cardiovascular disease. Previous studies
have indicated that ATP-binding cassette transporter A1 (ABCA1) is one of the most …

Peroxisome proliferator‐activated receptors and the heart: lessons from the past and future directions

WS Lee, J Kim - PPAR research, 2015 - Wiley Online Library
Peroxisome proliferator‐activated receptors (PPARs) belong to the nuclear family of ligand
activated transcriptional factors and comprise three different isoforms, PPAR‐α, PPAR‐β/δ …

Effects of exercise on reverse cholesterol transport: A systemized narrative review of animal studies

S Rahmati-Ahmadabad, DR Broom, A Ghanbari-Niaki… - Life sciences, 2019 - Elsevier
Abstract Aims Reverse Cholesterol Transport (RCTr) is the mechanism by which excess
cholesterol from peripheral tissues is transported to the liver for hepatobiliary excretion …

High-intensity interval training has a greater effect on reverse cholesterol transport elements compared with moderate-intensity continuous training in obese male rats

S Rahmati-Ahmadabad, MA Azarbayjani… - European journal of …, 2021 - academic.oup.com
Objectives The present study compares the effect of high-intensity interval training (HIIT; 18
min) and moderate-intensity continuous training (MIT; 1 h) on reverse cholesterol transport …

The effects of high-intensity interval training on reverse cholesterol transport elements: A way of cardiovascular protection against atherosclerosis

S Rahmati-Ahmadabad, H Shirvani, A Ghanbari-Niaki… - Life sciences, 2018 - Elsevier
Aims Reverse cholesterol transport (RCT) is a process that prevents atherosclerosis. Studies
showed that exercise training for strengthening cardiac muscle, increasing heart lipid …

Regular treadmill exercise inhibits mitochondrial accumulation of cholesterol and oxysterols during myocardial ischemia-reperfusion in wild-type and ob/ob mice

J Musman, S Pons, C Barau, C Caccia, V Leoni… - Free Radical Biology …, 2016 - Elsevier
Mitochondria play a central role in the irreversible damages induced to the heart by a
prolonged period of ischemia followed by reperfusion. We previously demonstrated that (1) …

Association of a Novel Homozygous Variant in ABCA1 Gene with Tangier Disease

S Barbosa-Gouveia, S Fernández-Crespo… - Journal of Clinical …, 2023 - mdpi.com
Tangier disease (TD) is a rare autosomal recessive disorder caused by a variant in the
ABCA1 gene, characterized by significantly reduced levels of plasma high-density …

The interaction between ABCA1 polymorphism and physical activity on the HDL-cholesterol levels in a Japanese population

Y Nishida, T Hachiya, M Hara, C Shimanoe… - Journal of lipid …, 2020 - ASBMB
Few studies have investigated the interactions between HDL-C-related SNPs identified by
genome-wide association (GWA) study and physical activity (PA) on HDL-C. First, we …

Medicinal plants and atherosclerosis: a review on molecular aspects

S Gholipour, RDE Sewell, Z Lorigooini… - Current …, 2018 - ingentaconnect.com
Atherosclerosis is an inflammatory vascular disease that is characterized by progressive
accumulation of cholesterol in the arterial walls and it is a major cause of cardiovascular …