Estimation of health risks associated with dietary cadmium exposure

S Satarug, DA Vesey, GC Gobe, KR Phelps - Archives of Toxicology, 2023 - Springer
In much of the world, currently employed upper limits of tolerable intake and acceptable
excretion of cadmium (Cd)(ECd/Ecr) are 0.83 µg/kg body weight/day and 5.24 µg/g …

Association between heavy metals, metalloids and metabolic syndrome: new insights and approaches

AC Martins, B Ferrer, AA Tinkov, S Caito… - Toxics, 2023 - mdpi.com
Metabolic syndrome (MetS) is an important public health issue that affects millions of people
around the world and is growing to pandemic-like proportions. This syndrome is defined by …

In silico identification of molecular mechanisms for stroke risk caused by heavy metals and their mixtures: Sponges and drugs involved

HD Nguyen, MS Kim - Neurotoxicology, 2023 - Elsevier
This study used various approaches and databases to evaluate the molecular processes
and identify miRNA sponges and drugs associated with the pathophysiology of stroke …

Is Environmental Cadmium Exposure Causally Related to Diabetes and Obesity?

S Satarug - Cells, 2023 - mdpi.com
Cadmium (Cd) is a pervasive toxic metal, present in most food types, cigarette smoke, and
air. Most cells in the body will assimilate Cd, as its charge and ionic radius are similar to the …

[HTML][HTML] Enhancers of mesenchymal stem cell stemness and therapeutic potency

M Al-Azab, E Idiiatullina, M Safi, K Hezam - Biomedicine & …, 2023 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a
range of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. Multiple …

White adipose tissue as a target for cadmium toxicity

SM Attia, SC Das, K Varadharajan… - Frontiers in …, 2022 - frontiersin.org
Cadmium (Cd) is a widespread heavy metal known as a toxic environmental pollutant. Cd
exposure is threatening due to its bioaccumulation trait in living systems that exceeds 35 …

[HTML][HTML] Arsenic induces metabolome remodeling in mature human adipocytes

M Gasser, S Lenglet, N Bararpour, T Sajic, J Vaucher… - Toxicology, 2023 - Elsevier
Human lifetime exposure to arsenic through drinking water, food supply or industrial
pollution leads to its accumulation in many organs such as liver, kidneys, lungs or pancreas …

Mitigation of cadmium toxicity through modulation of the frontline cellular stress response

S Satarug, DA Vesey, GC Gobe - Stresses, 2022 - mdpi.com
Cadmium (Cd) is an environmental toxicant of public health significance worldwide. Diet is
the main Cd exposure source in the non-occupationally exposed and non-smoking …

Evaluating combined effects of chronic, low-dose exposures of cadmium (CLEC) and hyperglycemia on insulin signaling dysfunction in a hepatocellular model

R Kumar, RR Gullapalli - Toxicology, 2024 - Elsevier
The pathophysiological effects of chronic heavy metal exposures on human health remains
uncertain. In this study, we developed a novel chronic, low-dose exposure of Cadmium …

Subacute cadmium exposure changes different metabolic functions, leading to type 1 and 2 diabetes mellitus features in female rats

CS da Costa, TF de Oliveira… - Environmental …, 2024 - Wiley Online Library
Cadmium (Cd) is a heavy metal that acts as endocrine disrupting chemical (EDC). Few
studies have investigated the effects of Cd exposure on metabolic dysfunctions, such as type …