Natural killer (NK) cells, a subgroup of innate lymphoid cells, act as the first line of defense
against cancer. Although some evidence shows that NK cells can develop in secondary …

Natural killer (NK) cells belong to the innate immune system and contribute to protecting the
host through killing of infected, foreign, stressed or transformed cells. Additionally, via …

Metastasis remains a pivotal characteristic of cancer and is the primary contributor to cancer-
associated mortality. Despite its significance, the mechanisms governing metastasis are not …

The neuronal ceroid lipofuscinoses (NCLs), also referred to as Batten disease, are a family
of neurodegenerative diseases that affect all age groups and ethnicities around the globe. At …

Simple Summary Natural killer (NK) cells are circulating innate lymphocytes endowed with
antitumoral functions. NK cells are the innate counterpart of effector T cells and among the …

Progranulin (PGRN) is a growth factor that is involved in the progression of multiple tumors.
However, the effects and molecular mechanisms by which PGRN induces lung cancer …

NK cells are promising cellular therapeutics against hematological and solid malignancies.
Immunogenetic studies have identified that various activating killer cell Ig-like receptors …

Breast cancer constitute a common type of oncological disease with a highlighted mortality
rate. In recent years, researchers have introduced progranulin (PGRN) as an novel potential …

Under normal conditions, the human body employs the synergistic action of osteoblasts and
osteoclasts to maintain a dynamic balance between bone formation and resorption. Bone …

We have recently demonstrated that invasive melanoma cells are capable of disrupting the
brain endothelial barrier integrity. This was shown using ECIS biosensor technology, which …