DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …

Sensors are devices that respond to physical or chemical stimuli and produce detectable
signals. 1r4 They are a critical extension of human perception of the world in many aspects …

In biology, nucleic acids are carriers of molecular information: DNA's base sequence stores
and imparts genetic instructions, while RNA's sequence plays the role of a messenger and a …

The reaction sequences of central metabolism, glycolysis and the pentose phosphate
pathway provide essential precursors for nucleic acids, amino acids and lipids. However …

Six new 5-position modified dUTP derivatives connected by a unique amide linkage were
synthesized and tested for compatibility with the enzymatic steps of in vitro selection. Six …

The unique chiral structure of DNA has been a source of inspiration for the development of a
new class of bio-inspired catalysts. The novel concept of DNA-based asymmetric catalysis …

Lyases are enzymes that catalyze the bond construction and breaking by means other than
hydrolysis or redox reactions. Such enzymes are particular in the sense that they only …

It has been 40 years since Spiegelman and co‐workers demonstrated how RNA molecules
can be evolved in the test tube. This result established Darwinian evolution as a chemical …

Deoxyribozymes or DNAzymes are single-stranded catalytic DNA molecules that are
obtained by combinatorial in vitro selection methods. Initially conceived to function as gene …

Taking the plunge: The first example of a Lewis acid catalyzed asymmetric Friedel–Crafts
alkylation with olefins in water is described. By using loadings of a DNA‐based copper …