A balanced act: The effects of GH–GHR–IGF1 Axis on mitochondrial function

B Hu, H Li, X Zhang - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Mitochondrial function is multifaceted in response to cellular energy homeostasis and
metabolism, with the generation of adenosine triphosphate (ATP) through the oxidative …

Current Evidence for a Role of Neuropeptides in the Regulation of Autophagy

E Catalani, C De Palma, C Perrotta… - BioMed research …, 2017 - Wiley Online Library
Neuropeptides drive a wide diversity of biological actions and mediate multiple regulatory
functions involving all organ systems. They modulate intercellular signalling in the central …

The effect of treatment on quality of life in patients with acromegaly: a prospective study

TLC Wolters, SHPP Roerink… - European journal of …, 2020 - academic.oup.com
Objective Acromegaly has a negative influence on health-related quality of life (HRQoL).
Previous studies provide limited information on the course of HRQoL during treatment. This …

[HTML][HTML] Resistant starch prevents tumorigenesis of dimethylhydrazine-induced colon tumors via regulation of an ER stress-mediated mitochondrial apoptosis pathway

Q Wang, P Wang, Z Xiao - International Journal of …, 2018 - spandidos-publications.com
Resistant starch is as common soluble fiber that escapes digestion in the small intestine and
can regulate intestinal function, metabolism of blood glucose and lipids, and may prevent …

Synergistic effect of apigenin and curcumin on apoptosis, paraptosis and autophagy-related cell death in HeLa cells

S Kayacan, K Yilancioglu, AS Akdemir… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: We aimed to investigate the synergistic effects of apigenin and curcumin
on the cross-talk between apoptosis and autophagic cell death, as well as on paraptosis in …

Autophagy in normal pituitary and pituitary tumor cells and its potential role in the actions of somatostatin receptor ligands in acromegaly

G Tulipano, A Giustina - Reviews in Endocrine and Metabolic Disorders, 2021 - Springer
Autophagy is an evolutionary conserved process for the self-degradation and recycling of
cellular components in the cytoplasm. It is involved in both physiological and pathological …

Architects of pituitary tumour growth

ME Sabatino, E Grondona, AL De Paul - Frontiers in endocrinology, 2022 - frontiersin.org
The pituitary is a master gland responsible for the modulation of critical endocrine functions.
Pituitary neuroendocrine tumours (PitNETs) display a considerable prevalence of 1/1106 …

Ultrastructural and molecular evidence of macroautophagy in functioning PitNETs and experimental pituitary tumors

LA Cecenarro, GD Moyano Crespo, CB Guido… - …, 2023 - karger.com
Introduction: Macroautophagy is a lysosome-mediated degradation process that controls the
quality of cytoplasmic components and organelles, with its regulation depending on …

Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5

Y Wang, X Zhang, W Chen, L Gao, J Li, T Song, J Chi… - Life sciences, 2020 - Elsevier
Aims Vascular smooth muscle cell (VSMC) proliferation plays a significant role in the
development of various vascular disorders. However, the effect of cortistatin (CST) on VSMC …

The effect of somatostatin analogues on Ki-67 levels in GH-secreting adenomas

A Selek, B Cetinarslan, Z Canturk, I Tarkun… - Growth Hormone & IGF …, 2019 - Elsevier
Abstract Purpose Somatostatin analogues (SSAs) can slow down the growth of
neuroendocrine tumors. However, the mechanism remains unclear. Recent studies on …