Depression and obesity: evidence of shared biological mechanisms
Depression and obesity are common conditions with major public health implications that
tend to co-occur within individuals. The relationship between these conditions is …
tend to co-occur within individuals. The relationship between these conditions is …
Depression heterogeneity and its biological underpinnings: toward immunometabolic depression
Y Milaneschi, F Lamers, M Berk, BWJH Penninx - Biological psychiatry, 2020 - Elsevier
Epidemiological evidence indicates the presence of dysregulated homeostatic biological
pathways in depressed patients, such as increased inflammation and disrupted energy …
pathways in depressed patients, such as increased inflammation and disrupted energy …
Metabolic and inflammatory markers: associations with individual depressive symptoms
BackgroundLiterature has shown that obesity, metabolic syndrome and inflammation are
associated with depression, however, evidence suggests that these associations are …
associated with depression, however, evidence suggests that these associations are …
Mood, the circadian system, and melanopsin retinal ganglion cells
L Lazzerini Ospri, G Prusky… - Annual review of …, 2017 - annualreviews.org
The discovery of a third type of photoreceptors in the mammalian retina, intrinsically
photosensitive retinal ganglion cells (ipRGCs), has had a revolutionary impact on …
photosensitive retinal ganglion cells (ipRGCs), has had a revolutionary impact on …
Comorbid generalized anxiety disorder and its association with quality of life in patients with major depressive disorder
Y Zhou, Z Cao, M Yang, X Xi, Y Guo, M Fang… - Scientific reports, 2017 - nature.com
The comorbidity of major depressive disorder (MDD) and generalized anxiety disorder
(GAD) is common and often predicts poorer outcomes than either disorder alone. This study …
(GAD) is common and often predicts poorer outcomes than either disorder alone. This study …
[HTML][HTML] Depression profilers and immuno-metabolic dysregulation: Longitudinal results from the NESDA study
F Lamers, Y Milaneschi, CH Vinkers… - Brain, Behavior, and …, 2020 - Elsevier
Background Major depressive disorder (MDD) is linked to higher cardio-metabolic
comorbidity that may in part be due to the low-grade inflammation and poorer metabolic …
comorbidity that may in part be due to the low-grade inflammation and poorer metabolic …
Replication and reproducibility issues in the relationship between C-reactive protein and depression: a systematic review and focused meta-analysis
One of the most common inflammatory markers examined in depression is C-reactive
protein (CRP). However, the magnitude of the association between CRP and depression …
protein (CRP). However, the magnitude of the association between CRP and depression …
Differentiating melancholic and non-melancholic depression via biological markers: A review
MJ Spoelma, A Serafimovska… - The World Journal of …, 2023 - Taylor & Francis
Objectives Melancholia is a severe form of depression that is typified by greater genetic and
biological influence, distinct symptomatology, and preferential response to physical …
biological influence, distinct symptomatology, and preferential response to physical …
How handling extreme C-reactive protein (CRP) values and regularization influences CRP and depression criteria associations in network analyses
Increasingly, it has been recognized that analysis at the symptom, rather than diagnostic,
level will drive progress in the field of immunopsychiatry. Network analysis offers a useful …
level will drive progress in the field of immunopsychiatry. Network analysis offers a useful …
Integrative modeling of accelerometry-derived sleep, physical activity, and circadian rhythm domains with current or remitted major depression
Importance Accelerometry has been increasingly used as an objective index of sleep,
physical activity, and circadian rhythms in people with mood disorders. However, most prior …
physical activity, and circadian rhythms in people with mood disorders. However, most prior …